Traditional and color M-mode parameters of left ventricular diastolic function during low-dose dobutamine stress echocardiography: relations to contractility reserve

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
Vittorio PalmieriRiccardo Pini

Abstract

Cross-sectional studies reported that left ventricular (LV) systolic and diastolic functions are correlated. However, whether changes in wall-motion score index (WMSI) or 2-dimensional ejection fraction (EF) predict changes of Doppler parameters of LV diastolic function is unclear. Patients with known or suspected history of coronary artery disease underwent assessment of LV systolic function (WMSI, EF) and diastolic function at baseline and during stress echocardiography by low-dose dobutamine (LDD) (peak infusion 10 microg/kg/min). Peak velocities of early (E) and late (A) LV filling waves and E wave deceleration time were measured according to standard protocol. E wave propagation rate (EVp) was assessed by color Doppler M-mode across the mitral valve. Tei index was calculated as: (A wave to E wave time - ejection time)/ejection time. Changes at LDD were calculated as: 100 x (value at LDD - value at baseline)/baseline. The study group comprised 66 patients, mean age 61 +/- 10 years, 80% men. Worse LV systolic function was associated with more severely impaired LV diastolic function both at baseline and at LDD. However, percent change of WMSI and change in EF did not correlate with percent change of EVp and E/E wave propagati...Continue Reading

References

Nov 1, 1989·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·P D BourdillonH Feigenbaum
Mar 1, 1986·Journal of the American College of Cardiology·M L LadenheimG A Diamond
Jun 1, 1983·British Heart Journal·P J OldershawD G Gibson
May 1, 1997·Journal of the American College of Cardiology·A M Duval-MoulinJ L Dubois-Randé
Jun 17, 1999·Archives of Internal Medicine·W B KannelD Levy
Nov 18, 2000·Journal of the American College of Cardiology·M S FirstenbergJ D Thomas
Jun 29, 2004·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Betina NøragerKenneth Egstrup
Feb 1, 2005·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Vittorio PalmieriAldo Celentano
Apr 23, 2005·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Rainer HoffmannPeter Hanrath

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