Traditional corticosteroids for induction of remission in Crohn's disease.

The Cochrane Database of Systematic Reviews
E I BenchimolA M Griffiths

Abstract

Historically, corticosteroids have been the most commonly used class of medication for induction of remission in Crohn's disease (CD). Corticosteroids down regulate production of inflammatory cytokines and interfere with NF-kappaB production, thereby blunting inflammatory response. The primary objective was to systematically review the efficacy and safety of traditional corticosteroids (given orally or intravenously) for induction of remission in CD. The following electronic databases were searched: MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, the Cochrane Inflammatory Bowel Disease and Functional Bowel Disorders (IBD/FBD) Group Specialized Trial Register, and ClinicalTrials.gov. No language restrictions were applied. Reference lists of trials and review articles, as well as recent proceedings from major gastroenterology meetings were manually searched. Randomized, controlled clinical trials of traditional, systemic corticosteroids for the induction of remission of active CD were included in this review. Control groups included patients receiving either placebo or 5-aminosalicylates (5-ASA). The study population included patients of any age with active CD (as defined by the study authors or validated cli...Continue Reading

References

Apr 1, 1992·Journal of Clinical Gastroenterology·P SalomonH D Janowitz
May 1, 1991·Journal of Pediatric Gastroenterology and Nutrition·J S HyamsJ T Boyle
Nov 8, 1985·Deutsche medizinische Wochenschrift·M U SchneiderJ F Riemann
Mar 8, 1980·Lancet·R F Harvey, J M Bradshaw
Apr 1, 1980·Gut·P A van HeesJ H van Tongeren
Dec 1, 1993·Trends in Pharmacological Sciences·P J Barnes, I Adcock
Aug 1, 1994·Alimentary Pharmacology & Therapeutics·C BrignolaL Barbara
Feb 1, 1996·Controlled Clinical Trials·A R JadadH J McQuay
Feb 24, 1999·The European Journal of Surgery = Acta Chirurgica·B G Feagan
Sep 30, 1999·Controlled Clinical Trials·H D ClarkA Laupacis
Oct 6, 2000·Current Opinion in Pediatrics·J S Hyams
Jul 7, 2001·BMJ : British Medical Journal·P JüniM Egger
May 11, 2002·The American Journal of Gastroenterology·Yu-Xiao Yang, Gary R Lichtenstein
Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Aug 14, 1954·British Medical Journal·S C TRUELOVE, L J WITTS
May 1, 2004·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Stephen B Hanauer, Ulf Strömberg
Jul 6, 2004·Alimentary Pharmacology & Therapeutics·J R Bebb, B B Scott
Jan 28, 2005·The Cochrane Database of Systematic Reviews·A K Akobeng, E Gardener
May 21, 2005·Inflammatory Bowel Diseases·Stephen B Hanauer
May 21, 2005·Inflammatory Bowel Diseases·Eduard F Stange
May 21, 2005·Inflammatory Bowel Diseases·Michael A Kamm
Sep 6, 2005·Pediatrics in Review·Jeffrey S Hyams
Oct 20, 2005·The Cochrane Database of Systematic Reviews·A Otley, A H Steinhart
Aug 31, 2006·Alimentary Pharmacology & Therapeutics·P Desreumaux, S Ghosh
Sep 12, 2006·Alimentary Pharmacology & Therapeutics·M A Kamm
Jan 27, 2007·The Cochrane Database of Systematic Reviews·M ZachosA M Griffiths
May 15, 2007·Lancet·Daniel C Baumgart, William J Sandborn

❮ Previous
Next ❯

Citations

Oct 24, 2012·Journal of Gastroenterology·Fumiaki UenoUNKNOWN Guidelines Project Group of the Research Group of Intractable Inflammatory Bowel Disease subsidized by the Ministry of Healt
Apr 30, 2011·World Journal of Gastroenterology : WJG·Paolo GionchettiFernando Rizzello
Oct 24, 2013·World Journal of Gastroenterology : WJG·Adam V Weizman, Geoffrey C Nguyen
Dec 5, 2016·Lancet·Joana TorresLaurent Peyrin-Biroulet
Jun 6, 2009·Chest·Alberto PapiPeter J Barnes
Feb 9, 2016·World Journal of Gastrointestinal Pharmacology and Therapeutics·Gerda C Leitner, Harald Vogelsang
Oct 21, 2017·Therapeutic Advances in Gastroenterology·Marcel Vetter, Markus F Neurath
Jan 21, 2014·The Cochrane Database of Systematic Reviews·Sushil K GargPeter Bager
Nov 11, 2011·The Cochrane Database of Systematic Reviews·Lee RothNilesh Chande
Jun 6, 2018·Digestion·Marcel Vetter, Markus F Neurath
Nov 12, 2009·Current Gastroenterology Reports·Cynthia H SeowRemo Panaccione
Jan 22, 2009·Molecular Nutrition & Food Research·Jirina HofmanováAlois Kozubík
Sep 11, 2014·Digestive Diseases and Sciences·Ashwin N Ananthakrishnan
Apr 11, 2012·Journal of Crohn's & Colitis·Remo PanaccioneStefan Schreiber
Sep 11, 2014·World Journal of Gastroenterology : WJG·Soo Jung ParkJae Hee Cheon
Mar 31, 2015·Journal of Gastroenterology and Hepatology·Choon Jin OoiUNKNOWN Asia Pacific Association of Gastroenterology (APAGE) Working Group on Inflammatory Bowel Disease
Mar 15, 2020·Journal of Crohn's & Colitis·Alexander M DorringtonTim Raine
Apr 24, 2010·Journal of Gastroenterology·Gargi Shikhare, Subra Kugathasan
Jul 12, 2020·Journal of Crohn's & Colitis·Femke CrouwelNanne K de Boer
Aug 19, 2020·Journal of the Pediatric Infectious Diseases Society·Daniel E DulekHamid Bassiri
Dec 3, 2016·Gastroenterology Report·Charumathi Raghu Subramanian, George Triadafilopoulos
Feb 13, 2018·Journal of Gastroenterology·Katsuyoshi MatsuokaTooru Shimosegawa
Apr 26, 2013·MMW Fortschritte der Medizin·R AtreyaM F Neurath
Mar 7, 2021·Pathogens·Martina FranzinGabriele Stocco
Apr 29, 2021·Frontline Gastroenterology·Jonathan BlackwellRichard Pollok
Nov 3, 2021·Der Internist·Carolin F MantheySamuel Huber

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrophic Gastritis

Atrophic Gastritis is a process where gastric glandular cells are lost and replaced with firbous tissues, as a result of chronic inflammation. Learn more about Atrophic Gastritis here.