Traffic Congestion as a Risk Factor for Mortality in Near-Road Communities: A Case-Crossover Study

American Journal of Epidemiology
Meredith PeddeSara D Adar

Abstract

Existing epidemiologic research on traffic largely neglects localized fluctuations. We leveraged finely resolved congestion data to investigate short-term associations with mortality in communities near roadways. We identified all nonaccidental, cardiovascular, cerebrovascular, and respiratory deaths (2009-2013) within 1 km of a highway in the Puget Sound region of Washington State. Using a case-crossover design, we examined the association of congestion 0-150 m, 151-300 m, and 301-1,000 m upwind of a decedent's home with mortality, adjusting for meteorology, holidays, and influenza activity. Among 9,449 deaths, we observed higher odds of cerebrovascular and respiratory mortality with greater upwind congestion, especially congestion near the decedent's home. For each 10-minute-km increase in upwind congestion within 150 m, the odds of cerebrovascular mortality were 1.08 (95% confidence interval (CI): 0.88, 1.33); within 151-300 m, the odds of cerebrovascular mortality were 1.05 (95% CI: 0.98, 1.12) times higher. We observed similar patterns for respiratory mortality, with 1.06 (95% CI: 0.76, 1.50) times higher odds of death with greater upwind congestion within 150 m and 1.02 (95% CI: 0.95, 1.10) times higher odds within 151-30...Continue Reading

References

Jul 1, 1995·American Journal of Epidemiology·M A MittlemanJ M Robins
Oct 1, 1996·Journal of Cardiovascular Risk·M W Knuiman, H T Vu
Feb 12, 2002·Environmental Health Perspectives·Yun-Chul HongDavid C Christiani
Sep 7, 2002·Stroke; a Journal of Cerebral Circulation·Yun-Chul HongHo-Jang Kwon
Sep 20, 2002·Journal of Epidemiology and Community Health·A Le TertreK Katsouyanni
Sep 25, 2002·Journal of the Air & Waste Management Association·Yifang ZhuConstantinos Sioutas
Nov 15, 2003·Stroke; a Journal of Cerebral Circulation·Ravi Maheswaran, Paul Elliott
Dec 4, 2003·Journal of Occupational Health·Haidong KanBingheng Chen
Oct 22, 2004·The New England Journal of Medicine·Annette PetersUNKNOWN Cooperative Health Research in the Region of Augsburg Study Group
Dec 18, 2004·Stroke; a Journal of Cerebral Circulation·Ravi MaheswaranMichael J Campbell
Feb 17, 2007·Stroke; a Journal of Cerebral Circulation·Jaana KettunenJuha Pekkanen
Apr 24, 2007·Environmental Health Perspectives·Sara Dubowsky AdarHelen Suh
Jul 20, 2007·Circulation·B HoffmannUNKNOWN Heinz Nixdorf Recall Study Investigative Group
Feb 22, 2008·Environmental Health Perspectives·Rob BeelenBert Brunekreef
Oct 23, 2008·The American Journal of Cardiology·C Arden PopeBenjamin D Horne
Feb 6, 2009·Environmental Research·Ryan W AllenSara D Adar
May 12, 2010·Circulation·Robert D BrookUNKNOWN American Heart Association Council on Epidemiology and Prevention, Council on the Kidney in Cardiovascular Disease, and Coun
Jan 27, 2011·European Heart Journal·Mette SørensenOle Raaschou-Nielsen
Feb 18, 2012·JAMA : the Journal of the American Medical Association·Hazrije MustaficXavier Jouven
Mar 13, 2014·European Journal of Preventive Cardiology·A TobíasC Linares

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