Training-related improvements in musculoskeletal health and balance: a 13-week pilot study of female cancer survivors

European Journal of Cancer Care
H C AlmstedtH P Tarleton

Abstract

Cancer survivors often experience poor post-treatment musculoskeletal health. This study examined the feasibility of combined aerobic and resistant training (CART) for improving strength, skeletal health and balance. Cancer survivors (n = 24) were identified by convenience sampling in Los Angeles County with 11 survivors consenting to 13 weeks of CART. Pre- and post-intervention assessments of bone mineral density (BMD), strength, flexibility and biomarker analysis were performed. Paired t-test analysis suggested increases in lower and upper body strength. The average T-score for BMD at the femoral neck improved from -1.46 to -1.36 and whole body BMD improved from -1.65 to -1.55. From baseline to follow-up, participants also displayed decreases in sway velocity on the eyes open (7%) and eyes closed (27%) conditions. Improvement in lower body strength was associated with increases in lean body mass (LBM) (r = 0.721) and an inverse association was observed between sway velocity and LBM (r = 0.838). Age and time since last treatment were related with biomarkers of anabolic growth (IGF-1, IGFbp-3) and bone (DPD, BAP). In summary, observed physiological changes were consistent with functional improvements, suggesting that isometric ...Continue Reading

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Citations

Oct 27, 2016·Archives of Physical Medicine and Rehabilitation·Nicole L StoutLeighton Chan
Jul 26, 2018·Integrative Cancer Therapies·Shinichiro MorishitaTetsuya Tsuji
Mar 1, 2019·Journal of Cachexia, Sarcopenia and Muscle·Miguel S Conceição, Carlos Ugrinowitsch
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Jan 22, 2020·Journal of Bioenergetics and Biomembranes·Somayeh YousefiAli Akbar Pourfathollah
Apr 1, 2021·Integrative Cancer Therapies·Jennifer Blackwood, Kateri Rybicki
Aug 16, 2021·Journal of Bodywork and Movement Therapies·Cristina Faustino CuvienaElaine Caldeira de Oliveira Guirro

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