Traits of selected Clostridium strains for syngas fermentation to ethanol

Biotechnology and Bioengineering
Michael E MartinLargus T Angenent

Abstract

Syngas fermentation is an anaerobic bioprocess that could become industrially relevant as a biorefinery platform for sustainable production of fuels and chemicals. An important prerequisite for commercialization is adequate performance of the biocatalyst (i.e., sufficiently high production rate, titer, selectivity, yield, and stability of the fermentation). Here, we compared the performance of three potential candidate Clostridium strains in syngas-to-ethanol conversion: Clostridium ljungdahlii PETC, C. ljungdahlii ERI-2, and Clostridium autoethanogenum JA1-1. Experiments were conducted in a two-stage, continuously fed syngas-fermentation system that had been optimized for stable ethanol production. The two C. ljungdahlii strains performed similar to each other but different from C. autoethanogenum. When the pH value was lowered from 5.5 to 4.5 to induce solventogenesis, the cell-specific carbon monoxide and hydrogen consumption (similar rate for all strains at pH 5.5), severely decreased in JA1-1, but hardly in PETC and ERI-2. Ethanol production in strains PETC and ERI-2 remained relatively stable while the rate of acetate production decreased, resulting in a high ethanol/acetate ratio, but lower overall productivities. With J...Continue Reading

References

Apr 1, 1993·International Journal of Systematic Bacteriology·R S TannerD Yang
Sep 4, 2003·Genome Research·Li LiDavid S Roos
May 7, 2004·Biotechnology and Bioengineering·Rohit P DatarRandy S Lewis
Apr 3, 2007·Current Opinion in Biotechnology·Anne M HenstraAlfons J M Stams
Mar 20, 2008·Genome Research·Daniel R Zerbino, Ewan Birney
Aug 30, 2008·Bioprocess and Biosystems Engineering·Jacqueline L CotterAmy M Grunden
Sep 20, 2008·Biochimica Et Biophysica Acta·Stephen W Ragsdale, Elizabeth Pierce
Jan 26, 2010·Bioresource Technology·Pradeep Chaminda Munasinghe, Samir Kumar Khanal
Mar 30, 2010·Journal of Bioscience and Bioengineering·Dimple K KundiyanaMark R Wilkins
Jul 10, 2010·Proceedings of the National Academy of Sciences of the United States of America·Michael KöpkePeter Dürre
Aug 10, 2010·Journal of Industrial Microbiology & Biotechnology·Jyotisna Saxena, Ralph S Tanner
Aug 12, 2010·Bioscience, Biotechnology, and Biochemistry·Takashi OhshiroYoshikazu Izumi
Oct 5, 2010·Journal of Bacteriology·Christopher L HemmeJizhong Zhou
Jun 21, 2011·Applied and Environmental Microbiology·Michael KöpkeSéan D Simpson
Apr 11, 2012·Bioresource Technology·Haris Nalakath AbubackarChristian Kennes
Apr 18, 2012·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·Anton BankevichPavel A Pevzner
Nov 23, 2012·Biotechnology and Bioengineering·Jose M PerezLargus T Angenent
Feb 21, 2013·Bioinformatics·Alexey GurevichGlenn Tesler
May 29, 2013·Genome Biology·Martin HuntThomas D Otto
Sep 10, 2013·Bioresource Technology·Jie GaoRaymond L Huhnke
Dec 20, 2013·Environmental Technology·Frank R BengelsdorfPeter Dürre
May 28, 2014·Current Opinion in Biotechnology·Haythem LatifKarsten Zengler
Nov 21, 2014·Journal of Industrial Microbiology & Biotechnology·Catherine E IsomRalph S Tanner

❮ Previous
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Citations

Jul 28, 2016·Frontiers in Microbiology·Frank R BengelsdorfPeter Dürre
Jan 24, 2017·Metabolic Engineering·Fungmin LiewNigel P Minton
Mar 30, 2017·Trends in Biotechnology·Sylvia GildemynKorneel Rabaey
Mar 7, 2018·Biotechnology for Biofuels·Kaspar ValgepeaEsteban Marcellin
May 18, 2020·Applied and Environmental Microbiology·Zi-Yong LiuFu-Li Li
Sep 8, 2020·Journal of Industrial Microbiology & Biotechnology·Charlotte Anne VeesStefan Pflügl
Apr 19, 2018·Biochemical Society Transactions·Rupert O J NormanCharlie Hodgman
Oct 19, 2019·Biotechnology for Biofuels·Oscar Rosales-Calderon, Valdeir Arantes
Jan 12, 2021·Frontiers in Bioengineering and Biotechnology·Alexander Katsyv, Volker Müller
Jun 11, 2018·Bioresource Technology·Xiao SunRalph S Tanner
Mar 23, 2021·Frontiers in Bioengineering and Biotechnology·Maria HermannRalf Takors
Apr 20, 2021·Annual Review of Chemical and Biomolecular Engineering·Nick FacklerMichael Köpke
Dec 22, 2020·Trends in Biotechnology·Yonghao CuiKang Zhou

❮ Previous
Next ❯

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