Trajectory Groups of 24-Hour Systolic Blood Pressure After Acute Ischemic Stroke and Recurrent Vascular Events

Stroke; a Journal of Cerebral Circulation
Beom Joon KimHee-Joon Bae

Abstract

Background and Purpose- Blood pressure dynamics in patients with acute ischemic stroke may serve as an important modifiable and prognostic factor. Methods- A total of 8376 patients with acute ischemic stroke were studied from a prospective multicenter registry. Patients were eligible if they had been admitted within 24 hours of symptom onset and had ≥5 systolic blood pressure (SBP) measurements during the first 24 hours of hospitalization. SBP trajectory groups in the first 24 hours were identified using the TRAJ procedure in SAS software with delta-Bayesian Information Criterion and prespecified modeling parameters. Vascular events, including recurrent stroke, myocardial infarction, and death, were prospectively collected. The risk of having vascular events was calculated using the frailty model to adjust for clustering by hospital. Results- The group-based trajectory model classified patients with acute ischemic stroke into 5 SBP trajectory groups: low (22.3%), moderate (40.8%), rapidly stabilized (11.9%), acutely elevated (18.5%), and persistently high (6.4%) SBP. The risk of having vascular events was increased in the acutely elevated (hazard ratio, 1.28 [95% confidence interval, 1.12-1.47]) and the persistently high SBP gr...Continue Reading

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Citations

Jul 1, 2019·The Journal of Clinical Hypertension·Jie XuUNKNOWN BOSS Study Group
Feb 27, 2020·Stroke; a Journal of Cerebral Circulation·Kanta TanakaUNKNOWN CRCS-K Investigators and the SAMURAI Study Investigators
Jun 27, 2019·International Journal of Environmental Research and Public Health·Yongho JeeSung-Il Cho
Aug 9, 2020·Frontiers in Neurology·Andrew SilvermanNils H Petersen
Aug 8, 2020·Journal of the American Society of Nephrology : JASN·Young Su JooSeung Hyeok Han
Oct 13, 2020·Hypertension·Philip B GorelickRobert M Carey
Oct 13, 2019·International Journal of Cardiology. Hypertension·Philip B GorelickMuhammad U Farooq
Apr 1, 2021·Journal of the American Heart Association·Beom Joon KimHee-Joon Bae
Jul 6, 2021·Neurology Research International·Jaurès KamgangUlrick Sidney Kanmounye
Jul 24, 2021·The Journal of Clinical Hypertension·Simona LattanziMauro Silvestrini

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