Tramadol in traumatic brain injury: Should we continue to use it?

Journal of Anaesthesiology, Clinical Pharmacology
Saeed MahmoodRifat Latifi

Abstract

Tramadol is commonly used to treat moderate to moderately-severe pain in adults. We aimed to analyze the clinical relevance of tramadol use during weaning and extubation in patients with traumatic brain injury (TBI). A retrospective observational study was conducted and included all the intubated TBI patients at the level I trauma center between 2011 and 2012. Data included patient's demographics, mechanism of injury (MOI), Glasgow Coma Scale (GCS), injury severity score, length of Intensive Care Unit (ICU) stay length of stay (LOS), agitation scale, analgesics, failure of extubation and tracheostomy. Patients were divided into two groups based on whether they received tramadol (Group 1) or not (Group 2) during ventilatory weaning. Chi-square and Student's t-tests were used for categorical and continuous variables; respectively. Logistic regression analysis was performed for predictors of agitation in ICU. The study included 393 TBI patients; the majority (96%) was males with a mean age of 33.6 ± 14 years. The most common MOI were motor vehicle crash (39%), fall (29%) and pedestrian (17%). The associated injuries were mainly chest (35%) and abdominal (16%) trauma. Tramadol was administered in 51.4% of TBI patients. Tracheostomy...Continue Reading

References

Jan 1, 1997·Journal of Toxicology. Clinical Toxicology·H A SpillerD L Anderson
Aug 9, 2001·British Journal of Anaesthesia·H M SolimanJ L Vincent
May 25, 2007·Critical Care : the Official Journal of the Critical Care Forum·Jean-Claude Chevrolet, Philippe Jolliet
Jun 9, 2007·British Journal of Anaesthesia·A HelmyA K Gupta
Jun 17, 2008·Critical Care : the Official Journal of the Critical Care Forum·Wolfram Wilhelm, Sascha Kreuer
Jan 1, 2008·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Atul P Kulkarni, Vandana Agarwal

❮ Previous
Next ❯

Citations

Jan 29, 2016·Journal of Food Protection·Edward P C LaiTyler J Avis
Oct 12, 2019·Anesthesia, Essays and Researches·Saeed A MahmoodHassan A Al-Thani
Mar 27, 2018·World Journal of Emergency Medicine·Saeed MahmoodHassan Al-Thani

❮ Previous
Next ❯

Methods Mentioned

BETA
sedation
sedations
ISS

Software Mentioned

Statistical Package for Social Sciences

Related Concepts

Related Feeds

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.