Tranexamic Acid Combined with Compression Bandage Following Total Knee Arthroplasty Promotes Blood Coagulation: A Retrospective Analysis.

BioMed Research International
Guo-Hua LiFu Wang

Abstract

This paper included a retrospective review of the effect of tranexamic acid (TXA) combined with pressure bandaging on hemostasis of patients who received a unilateral total knee arthroplasty (TKA) from 2017 to 2019. A total of 197 patients undergoing TKA were chosen to be classified into 2 groups, the compression bandage control group and compression bandage combined with TXA observation group. The patients received blood routine examination when they were in the 1st, 3rd, and 6th days of before and postoperation. Some parameters, such as hemoglobin (Hb), C-reactive protein (CRP), D-dimer value, fibrinogen, prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), international normalized ratio (INR), and erythrocyte sedimentation rate (ESR), were also investigated. In our research, the mean age was 66.54 ± 7.95 years. No difference was found in patient sex (P = 0.876) and age (P = 0.749) between groups. No differences were found in the levels of Hb, fibrinogen, TT, and INR between the 2 groups at each period (P > 0.05). The difference of PT was significantly different on the 1st day (P = 0.011), 3rd day (P = 0.010), and 6th day (P = 0.004) after surgery. Besides, the changes in APTT in observatio...Continue Reading

References

Nov 12, 2015·Journal of Orthopaedic Surgery and Research·Genya MitaniJoji Mochida
Aug 15, 2017·Methods in Molecular Biology·Anetta Undas
May 29, 2018·Canadian Journal of Surgery. Journal Canadien De Chirurgie·Hossam El BeheiryVicky Sharma
Jun 20, 2018·Journal of Orthopaedic Surgery and Research·Andrea L GrantGeoffrey P Dobson
Mar 21, 2019·The Journal of Bone and Joint Surgery. American Volume·Sarah E RudasillAtul F Kamath
Apr 23, 2020·Medical Archives·Giovanni CappielloUmberto Ripani

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Citations

Jun 13, 2021·Journal of Orthopaedic Surgery and Research·Jimin MaQiang Wang

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ESR

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SPSS

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