trans-Cyclooctenes as Halolactonization Catalysts

Angewandte Chemie
Shunsuke EinaruSeijiro Matsubara

Abstract

The strained olefins in trans-cyclooctenes serve as efficient catalysts for halolactonizations, including bromolactonizations and iodolactonizations. The trans-cyclooctene framework is essential for excellent catalytic performance, and the substituents also play important roles in determining efficiency. These results are the first demonstration of catalysis by a trans-cyclooctene.

References

Mar 1, 1994·The Journal of Clinical Investigation·Y G WolfE Ruoslahti
Sep 1, 2005·Journal of the American Chemical Society·Katsuhiko TomookaSyun-ichi Yanagitsuru
Feb 1, 2008·Angewandte Chemie·Scott E Denmark, Gregory L Beutner
Feb 19, 2008·Journal of the American Chemical Society·Oleg V Larionov, E J Corey
Mar 7, 2008·Journal of the American Chemical Society·Maksim RoyzenJoseph M Fox
May 7, 2008·Angewandte Chemie·Christian DefieberErick M Carreira
Sep 19, 2008·Journal of the American Chemical Society·Melissa L BlackmanJoseph M Fox
Jan 12, 2010·Journal of the American Chemical Society·Scott E DenmarkAndrew J Hoover
Jun 23, 2010·Journal of the American Chemical Society·Katsuhiko TomookaKazunobu Igawa
Aug 14, 2010·Proceedings of the National Academy of Sciences of the United States of America·Scott E Denmark, Matthew T Burk
Apr 22, 2011·Chemistry : a European Journal·Alejandro Castellanos, Stephen P Fletcher
Jun 2, 2011·Accounts of Chemical Research·Neal K Devaraj, Ralph Weissleder
Feb 9, 2012·Chemistry, an Asian Journal·Ulrich Hennecke
Sep 15, 2012·Angewandte Chemie·Katsuhiko TomookaKazunobu Igawa
Sep 27, 2012·Angewandte Chemie·Scott E DenmarkMatthew T Burk
Aug 2, 2013·Chemical Communications : Chem Comm·Chong Kiat Tan, Ying-Yeung Yeung
Dec 18, 2013·Chirality·Chong Kiat TanYing-Yeung Yeung
Mar 7, 2014·Organic & Biomolecular Chemistry·Yi An ChengYing-Yeung Yeung
Oct 23, 2014·Journal of the American Chemical Society·Tomoya MiuraMasahiro Murakami
Feb 7, 2015·Angewandte Chemie·Brisa HurlockerK A Woerpel
Jun 19, 2015·Journal of the American Chemical Society·David N KamberJennifer A Prescher
Jul 7, 2015·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Akira Sakakura, Kazuaki Ishihara

❮ Previous
Next ❯

Citations

Aug 29, 2020·Chemical Communications : Chem Comm·Haripriyo MondalModhu Sudan Maji
Jul 6, 2021·Bioorganic & Medicinal Chemistry·Saraliny Bezerra FrançaDimas José da Paz Lima
Dec 12, 2018·The Journal of Organic Chemistry·Yan-Na MaXuenian Chen
Aug 27, 2019·The Journal of Organic Chemistry·Jørn Eivind TungenTrond Vidar Hansen
Jul 19, 2019·The Journal of Organic Chemistry·Rajendra K MallickAkhila K Sahoo
Oct 22, 2021·The Journal of Organic Chemistry·Kimberly M Hilby, Scott E Denmark

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.