trans-fatty acid isomers in adipose tissue have divergent associations with adiposity in humans.

Lipids
Liesbeth A SmitHannia Campos

Abstract

The aim of this study was to evaluate the association between adipose tissue trans-fatty acid isomers and adiposity. This cross-sectional study included 1,785 subjects from Costa Rica. Fatty acid concentrations (as a percentage of the total fatty acids) in subcutaneous adipose tissue were assessed by gas-liquid chromatography. Dietary intakes were assessed with a food frequency questionnaire. Multivariate linear regression models were used to relate adipose tissue trans-fatty acid content to BMI, waist circumference, and skinfold thickness while adjusting for age, sex, and area of residence. To account for variations in lifestyle, we adjusted for smoking, physical activity, income, self-reported history of diabetes and hypertension, and for adipose tissue alpha-linolenic acid and energy intake in a third model. After adjustments, positive associations were found between 18:2t-fatty acids (primarily from partially hydrogenated oils) and BMI, waist circumference, and skinfold thickness (P for each association <0.01). Rumenic acid was positively associated with skinfold thickness (P < 0.0001), but not with BMI or waist circumference (P > 0.05). Inverse associations were found between 16:1n-7t-fatty acids and skinfold thickness and...Continue Reading

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May 14, 2010·The American Journal of Clinical Nutrition·Liesbeth A SmitHannia Campos

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Citations

Jul 19, 2012·European Journal of Clinical Nutrition·C P HansenM U Jakobsen
Aug 4, 2011·PloS One·Christina Catherine DahmKim Overvad
Nov 30, 2013·The British Journal of Nutrition·Camilla P HansenMarianne U Jakobsen
Apr 2, 2015·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·K FeketeT Decsi
May 4, 2017·Journal of Lipid Research·Elom K AglagoVeronique Chajès
Feb 1, 2018·Human Fertility : Journal of the British Fertility Society·Hande Çekici, Yasemin Akdevelioğlu
Jun 2, 2020·The British Journal of Nutrition·Yinan HuaWeiwei Ma

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Methods Mentioned

BETA
biopsy

Software Mentioned

Agilent Technologies ChemStation
SAS

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