PMID: 6987058Feb 1, 1980Paper

Trans-membrane translocation of proteins. A detailed physico-chemical analysis

European Journal of Biochemistry
G von Heijne

Abstract

A detailed, computerized procedure for analysing the translocation process of any protein with known sequence from a physico-chemical point of view is presented and used to gain a better understanding of the molecular 'rules' that govern the final outcome of the process. With the aid of this prodedure a number of testable predictions of the orientations of particular membrane-bound proteins can be made. It is also suggested that ovalbumin, the only known secreted protein lacking a cleavable prepiece, initiates translocation in a way that differs from other secreted proteins.

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Citations

Aug 1, 1982·Planta·G W Bolton, P H Quail
Jan 1, 1983·The International Journal of Biochemistry·I Suominen, P Mäntsälä
May 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·M SchwartzM Débarbouillé
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Nov 2, 1983·European Journal of Biochemistry·U HenningH Schaller
Jan 1, 1986·CRC Critical Reviews in Biochemistry·T A Rapoport
Nov 28, 1980·Biochemical and Biophysical Research Communications·J C MercierM N Raymond
Jun 15, 1987·Biochemical and Biophysical Research Communications·K YoshimuraM Ikehara
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Feb 1, 1982·Journal of Dairy Science·J C Mercier, P Gaye
Mar 11, 2018·The Journal of Biological Chemistry·Gunnar von Heijne
Apr 27, 1987·Biochimica Et Biophysica Acta·M K Jain, D Zakim
Jan 1, 1982·Bio Systems·J A Raven, F A Smith
Jan 10, 1998·Biochemistry·J F HuntD M Engelman
Nov 21, 1980·Science·W Wickner

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