Trans-Species Polymorphism in Mitochondrial Genome of Camarodont Sea Urchins

Genes
Evgeniy S Balakirev

Abstract

Mitochondrial (mt) genomes of the sea urchins Strongylocentrotus intermedius and Mesocentrotus nudus demonstrate the identical patterns of intraspecific length variability of the ND6 gene, consisting of 489 bp (S variant) and 498 bp (L variant), respectively. For both species, the ND6 length difference is due to the 488A>G substitution, which changes the stop codon TAG in S variant for a tryptophan codon TGG in L variant and elongates the corresponding ND6 protein by three additional amino acids, Trp-Leu-Trp. The phylogenetic analysis based on mt genomes of sea urchins and related echinoderm groups from GenBank has shown the S and L ND6 variants as shared among the camarodont sea urchins; the rest of the echinoderms demonstrate the S variant only. The data suggest that the ND6 488A>G substitution can be the first example of the trans-species polymorphism in sea urchins, persisting at least since the time of the Odontophora diversification at the Eocene/Oligocene boundary (approximately 34 million years ago), which was characterized by an abrupt climate change and significant global ocean cooling. Alternative hypotheses, including the convergent RNA editing and/or codon reassignment, are not supported by direct comparisons of th...Continue Reading

References

Jun 1, 1978·The Journal of Experimental Zoology·P S LeahyE H Davidson
Oct 5, 1990·Journal of Molecular Biology·S F AltschulD J Lipman
Apr 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·N Takahata
Dec 10, 1971·Nature·J B CleggP F Milner
Jun 1, 1996·Current Genetics·Y Hayashi-IshimaruS Osawa
Nov 9, 2000·Biochemical Systematics and Ecology·G P Manchenko, S N Yakovlev
Nov 28, 2000·Annual Review of Genetics·J M Gott, R B Emeson
Feb 21, 1986·Science·D M Raup, J J Sepkoski
Jan 10, 2002·European Journal of Human Genetics : EJHG·K RavnM Schwartz
Feb 25, 2003·Molecular Biology and Evolution·Christophe J DouadyEmmanuel J P Douzery
Jun 26, 2003·Evolution & Development·Christiane H BiermannStephen R Palumbi
Nov 5, 2003·Proceedings of the National Academy of Sciences of the United States of America·Veronica F HinmanEric H Davidson
Jan 9, 2004·American Journal of Human Genetics·J L ElsonNeil Howell
Mar 12, 2004·Molecular Ecology·J William O Ballard, Michael C Whitlock
Mar 23, 2004·Nucleic Acids Research·Robert C Edgar
Nov 2, 2004·Familial Cancer·Joel Charrow
Aug 21, 2007·Journal of Genetics and Genomics = Yi Chuan Xue Bao·Shuqing XuXiaoguang Zheng
Dec 14, 2007·Annual Review of Genetics·Jan KleinNikolas Nikolaidis
Mar 6, 2008·BMC Genomics·Rute R da FonsecaAgostinho Antunes
Aug 30, 2008·Trends in Ecology & Evolution·Damian K DowlingJohan Lindell
Oct 15, 2008·Proceedings of the National Academy of Sciences of the United States of America·Evgeniy S BalakirevFrancisco J Ayala
Dec 4, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Katherine M BuckleyL Courtney Smith
Mar 3, 2009·Science·Zhonghui LiuAnn Pearson
Aug 27, 2009·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Willemijn M GommansStefan Maas
Jan 29, 2010·Molecular Biology and Evolution·Xuan Zhuang, C-H Christina Cheng
Mar 4, 2010·Genetics and Molecular Research : GMR·T NingY P Zhang
May 28, 2010·Nature·Rouslan G EfremovLeonid A Sazanov
Jun 9, 2010·Systematic Biology·Mette E SteemanEske Willerslev
Oct 13, 2010·Cellular and Molecular Life Sciences : CMLS·Volker Knoop
Feb 24, 2012·Systematic Biology·Fredrik RonquistJohn P Huelsenbeck
Jul 13, 2012·BMC Plant Biology·Evgeniy S BalakirevFrancisco J Ayala
Aug 1, 2012·Nature Methods·Diego DarribaDavid Posada
Jan 19, 2013·Molecular Biology and Evolution·Kazutaka Katoh, Daron M Standley

❮ Previous
Next ❯

Datasets Mentioned

BETA
KY964299.1
KY964300.1

Methods Mentioned

BETA
targeted modifications

Software Mentioned

MEGA
MEGA7
RDP4
MUSCLE
Protein Feature Server ( PROFEAT )
BLAST
jModelTest
MrBayes
MAFFT

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.