Transactional sex and incident HIV infection in a cohort of young women from rural South Africa.

AIDS
Kelly N KilburnAudrey Pettifor

Abstract

In sub-Saharan Africa, young women who engage in transactional sex (the exchange of sex for money or gifts) with a male partner show an elevated risk of prevalent HIV infection. We analyse longitudinal data to estimate the association between transactional sex and HIV incidence. We used longitudinal data from a cohort of 2362 HIV-negative young women (aged 13-20 years) enrolled in a randomized controlled trial in rural, South Africa who were followed for up to four visits over 6 years. The effect of transactional sex on incident HIV was analysed using stratified Cox proportional hazards models and cumulative incidence curves. Risk ratios were estimated using log-binomial models to compare the effects across visits. HIV incidence was higher for young women that reported transactional sex (hazard ratio 1.59, 95% confidence interval 1.02-2.19), particularly when money and/or gifts were received frequently (at least weekly) (hazard ratio 2.71, 95% confidence interval 1.44-5.12). We also find that effects were much stronger during the main trial and dissipate at the postintervention visit, despite an increase in both transactional sex and HIV. Transactional sex elevates the risk of HIV acquisition among young women, especially when ...Continue Reading

References

Feb 9, 2007·Developmental Science·Adriana GalvanB J Casey
Aug 7, 2008·American Journal of Epidemiology·Stephen R Cole, Miguel A Hernán
Jun 18, 2009·Current Opinion in HIV and AIDS·Frances Cowan, Audrey Pettifor
Jul 1, 2010·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Craig M WilsonBret Rudy
Mar 2, 2011·AIDS·Miles Q OttMarie-Louise Newell
Jan 24, 2012·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Stanley XuDavid Magid
Jun 29, 2013·Culture, Health & Sexuality·Erin Stern, Rosemarie Buikema
Mar 1, 2015·Journal of the International AIDS Society·Rachael C DellarQuarraisha Abdool Karim
Jul 30, 2016·Journal of the International AIDS Society·Meghna RanganathanCharlotte Watts
Nov 5, 2016·Journal of the International AIDS Society·Joyce WamoyiCharlotte Watts

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Citations

Feb 23, 2019·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Joyce WamoyiKirsten Stoebenau
Jul 30, 2019·Journal of the International AIDS Society·Danielle GiovencoJames P Hughes
Nov 13, 2019·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Meghna RanganathanAudrey Pettifor
Jul 9, 2020·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Katherine B RucinskiStefan D Baral
Apr 2, 2020·PloS One·Dimitris KarletsosMargaret McConnell
Dec 17, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marie C D StonerAudrey Pettifor
Feb 25, 2021·Journal of Public Health in Africa·Idris DurojaiyeLatifat Ibisomi
Nov 23, 2020·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Sophia Zamudio-HaasHong-Ha M Truong
Nov 30, 2021·PLoS Medicine·Marie C D StonerAudrey E Pettifor

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