Transapical mitral valved stent implantation

The Annals of Thoracic Surgery
Lucian LozonschiGeorg Lutter

Abstract

Transcatheter aortic and pulmonary valve replacement is currently being tested in human trials. Efforts to create a valved stent to replace the atrioventricular valves have shown limited success. This is due to their their complex anatomy and function. A self-expanding valved stent was created for transapical replacement of the atrioventricular valve. Ten pigs underwent transapical off-pump mitral valved stent implantation. Data were gathered to assess the animals' hemodynamic stability for 60 minutes after implantation. The valved stent function was assessed by transesophageal echocardiography (TEE) and contrast left ventriculogram. All animals exhibited normal hemodynamics immediately after mitral valved stent implantation and maintained stability for the entire period of monitoring. Accurate positioning of the valved stent was established in all animals. Mild paravalvular regurgitation was found in three out of ten animals by TEE and in two animals during left ventriculogram. No left ventricular outflow tract obstruction was encountered. Transapical off-pump mitral valved stent implantation is feasible in an acute experimental setting. Long-term function of the new valved stent remains to be established.

References

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Citations

Jul 13, 2011·Herz·S C BertogH Sievert
Feb 1, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Kenji IinoGeorg Lutter
Jul 24, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Yu ZouLudwig K von Segesser
Sep 17, 2013·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Ali AndalibNicolo Piazza
Jan 17, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Jan-Paul GundlachGeorg Lutter
Apr 22, 2014·Medical Engineering & Physics·Gideon Praveen KumarJimmy Kim Fatt Hon
Nov 26, 2013·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Saskia PokornyGeorg Lutter
Feb 8, 2011·The Journal of Thoracic and Cardiovascular Surgery·Eric BerreklouwFriedrich W Mohr
Mar 17, 2010·The Journal of Thoracic and Cardiovascular Surgery·Lucian LozonschiGeorg Lutter
Mar 30, 2010·The Journal of Thoracic and Cardiovascular Surgery·René Hubert BombienGeorg Lutter
Aug 14, 2010·Journal of the American College of Cardiology·Nicolas M Van MieghemPeter P de Jaegere
Apr 17, 2010·Journal of the American College of Cardiology·Shahbudin H Rahimtoola
Nov 5, 2014·Circulation·Howard C Herrmann, Francesco Maisano
Jun 20, 2014·Circulation. Cardiovascular Interventions·Ole De BackerLars Søndergaard
Dec 25, 2009·Circulation. Cardiovascular Interventions·Jean-Bernard Masson, John G Webb
Jan 3, 2013·Expert Review of Medical Devices·Jamshid H KarimovKiyotaka Fukamachi
Dec 4, 2019·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Georg LutterThomas Puehler
Mar 23, 2011·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Tim AttmannGeorg Lutter
Mar 29, 2018·Interactive Cardiovascular and Thoracic Surgery·Thang Duc VuTheo Kofidis
Jul 28, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Klaas LogerSaskia Pokorny
Dec 7, 2020·Interactive Cardiovascular and Thoracic Surgery·Georg LutterThomas Puehler

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