Transarterial chemoembolization as a substitute to radiofrequency ablation for treating Barcelona Clinic Liver Cancer stage 0/A hepatocellular carcinoma

Oncotarget
Kentaro IshikawaNaoya Kato

Abstract

Transarterial chemoembolization (TACE) is the standard procedure for treating Barcelona clinic liver cancer (BCLC) stage B hepatocellular carcinoma (HCC). However, it is often carried out in the treatment of BCLC stage 0/A HCC for various reasons. This study aimed to elucidate the prognosis for BCLC stage 0/A HCC patients treated with TACE or with radiofrequency ablation (RFA). The prognosis of 242 BCLC stage 0/A HCC patients within Milan criteria who underwent initially TACE or RFA were retrospectively analyzed using propensity score matching analysis. The analyses of baseline patient characteristics revealed that the maximum tumor size and the proportion of BCLC stage A patients were significantly higher in patients treated with TACE than in those treated with RFA (P<0.001 and 0.047, respectively). After adjusting these factors using propensity score matching (1:3 matching), patients treated with TACE (n=32) and those treated with RFA (n=96) were further analyzed. The local recurrence rate was significantly higher in the TACE group than in the RFA group (P<0.001). However, the overall survival (OS) in HCC patients treated with TACE was comparable to that in HCC patients treated with RFA (1 year, 93.5 vs. 95.8%; 3 years, 75.4 ...Continue Reading

References

Jul 27, 2001·Journal of Surgical Oncology·I D Fleming
Dec 12, 2003·Lancet·Josep M LlovetJordi Bruix
Feb 6, 2004·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Josep M LlovetUNKNOWN Barcelona-Clínic Liver Cancer Group
Mar 31, 2004·Cancer Cell·Jordi BruixJosep M Llovet
Feb 23, 2010·Seminars in Liver Disease·Riccardo Lencioni, Josep M Llovet
Dec 24, 2010·World Journal of Radiology·Yasunori Minami, Masatoshi Kudo
Feb 8, 2011·CA: a Cancer Journal for Clinicians·Ahmedin JemalDavid Forman
Mar 5, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jordi BruixUNKNOWN American Association for the Study of Liver Diseases
Apr 21, 2011·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Chia-Yang HsuShou-Dong Lee
Mar 20, 2012·Journal of Hepatology·UNKNOWN European Association For The Study Of The Liver, UNKNOWN European Organisation For Research And Treatment Of Cancer
Jan 15, 2014·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Young-Joo JinYong Sun Jeon
Jan 18, 2014·Seminars in Interventional Radiology·Shaunagh McDermott, Debra A Gervais
May 2, 2014·Seminars in Liver Disease·Jordan J Feld
Sep 16, 2014·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayFreddie Bray
Dec 17, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Philip J JohnsonHidenori Toyoda
Jan 7, 2015·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Tatsuya MinamiKazuhiko Koike

❮ Previous
Next ❯

Methods Mentioned

BETA
sedation

Software Mentioned

mRECIST

Related Concepts

Related Feeds

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.