Transcatheter Aortic Valve Replacement Using the Repositionable LOTUS Valve: United Kingdom Experience.

JACC. Cardiovascular Interventions
Rajiv RampatDavid Hildick-Smith

Abstract

This study sought to present the U.K. experience to date with the second-generation LOTUS bioprosthesis (Boston Scientific, Natick, Massachusetts). First-generation transcatheter aortic valves have limitations. Second-generation repositionable valves may improve on some of those limitations. Prospectively collected data relating to procedural and in-hospital outcome was analyzed from 10 implantation centers in the United Kingdom. Implants in 228 patients age 81.4 ± 7.6 years were studied; 53.5% were male. Mean logistic EuroScore was 17.5 ± 12.4. One hundred eighty-seven (82.0%) were undertaken for aortic stenosis, 7 (3.1%) for aortic regurgitation, and 34 (14.9%) for mixed aortic valve disease. A total of 67.1% of cases were done under local anesthetic and/or sedation with transfemoral access in 94.7% and transaortic in 5.3%. Three device sizes were used: 23 mm (n = 66, 28.9%), 25 mm (n = 39, 17.1%), and 27 mm (n = 123, 53.9%). The valve was successfully deployed in 99.1% of procedures. After implantation, the mean aortic gradient was 11.4 ± 5.4 mm Hg and aortic valve area 1.6 ± 0.5 cm(2). In-hospital mortality was 1.8% (n = 4). Complications included cardiac tamponade (1.8%), conversion to sternotomy (1.3%), stroke (3.9%), vas...Continue Reading

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Citations

Sep 10, 2016·Journal of the American College of Cardiology·Sung-Han YoonSeung-Jung Park
Feb 2, 2017·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Rocco A MontoneFrancesco Bedogni
Mar 4, 2017·Journal of Interventional Cardiology·Kishore J HarjaiSusheel Kodali
Nov 20, 2016·Journal of the American Heart Association·Thomas PilgrimStephan Windecker
Dec 12, 2018·Expert Review of Medical Devices·David Del ValJosep Rodés-Cabau
Jun 8, 2019·Expert Review of Medical Devices·Guillem Muntané-CarolJosep Rodés-Cabau
Jun 3, 2017·Expert Review of Medical Devices·Bruna GomesRaffi Bekeredjian
Sep 25, 2017·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Francesco GianniniAntonio Colombo
Sep 17, 2019·Journal of the American Heart Association·Roberto ScarsiniAdrian P Banning
Feb 20, 2016·JACC. Cardiovascular Interventions·Thomas Pilgrim, Stephan Windecker
Nov 19, 2021·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Ashan GunarathneKamran Baig

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