Transcatheter aortic valve replacement with the Lotus valve system

Future Cardiology
Colin M Barker, Michael J Reardon

Abstract

Transcatheter aortic valve replacement has become an acceptable alternative to surgical aortic valve replacement in patients who are intermediate to high risk for surgery. The Lotus™ valve system (Boston Scientific, MA, USA) is an unique, mechanically expanded device. The system includes a braided nitinol frame and an adaptive seal to minimize paravalvular regurgitation. REPRISE III illustrated that among high-risk patients the use of the Lotus valve compared with a self-expanding valve did not result in inferior outcomes for the primary safety end point or the primary effectiveness end point. Future investigation of the Lotus valve system includes the use in low to intermediate risk patients with aortic stenosis as well as those with bicuspid aortic valves and mitral annular calcification.

References

May 1, 2007·The Journal of Thoracic and Cardiovascular Surgery·Hans-H Sievers, Claudia Schmidtke
Feb 15, 2012·The Journal of Thoracic and Cardiovascular Surgery·Marian KukuckaAxel Unbehaun
Jul 14, 2012·The Thoracic and Cardiovascular Surgeon·Arnaud Van LindenThomas Walther
Apr 25, 2013·European Archives of Paediatric Dentistry : Official Journal of the European Academy of Paediatric Dentistry·W F KeysR R Welbury
Oct 31, 2013·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Ian T MeredithKeith D Dawkins

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Citations

Aug 10, 2020·Current Cardiology Reports·Taishi OkunoThomas Pilgrim
Apr 14, 2020·Current Pharmaceutical Design·M DrakopoulouΚ Toutouzas

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Clinical Trials Mentioned

NCT01383720
NCT01627691
NCT02031302
NCT02202434
NCT02491255
NCT02329496

Software Mentioned

Lotus
REPRISE IV
REPRISE
RESPOND

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