Transcatheter Aortic Valve Replacement With the HLT Meridian Valve

Circulation. Cardiovascular Interventions
Josep Rodés-CabauSpencer H Kubo

Abstract

While most self-expanding transcatheter valves are repositionable, only one fully retrievable valve is currently available. The Meridian valve is a new self-expanding valve with full retrievability properties. The objective of our study was to evaluate the early feasibility, preliminary safety, and efficacy of transcatheter aortic valve replacement with the HLT Meridian valve (HLT, Inc). This was a multicenter early feasibility study including patients with severe aortic stenosis at high surgical risk undergoing transfemoral transcatheter aortic valve replacement with the 25-mm Meridian valve. All serious adverse events were adjudicated by an independent clinical events committee according to Valve Academic Research Consortium-2 criteria. Echocardiography data were assessed by an independent echocardiography core laboratory. A total of 25 patients (mean age, 85±6 years; 80% of men) were included. The valve was successfully implanted in 22 (88%) patients (annulus too large and extreme horizontal aorta in 2 and 1 unsuccessful cases, respectively). Valve retrieval because of an initial nonadequate positioning was attempted and successfully performed in 10 (40%) patients. Echocardiography post-transcatheter aortic valve replacement...Continue Reading

References

Nov 16, 2011·Nature Reviews. Cardiology·Josep Rodés-Cabau
Dec 25, 2012·The Journal of Thoracic and Cardiovascular Surgery·Michael Mack
Oct 31, 2013·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Ian T MeredithKeith D Dawkins
Aug 16, 2016·Journal of the American College of Cardiology·Vincent AuffretJosep Rodés-Cabau
Apr 17, 2017·JACC. Cardiovascular Imaging·Yoshio MaenoHasan Jilaihawi
Aug 25, 2017·Nature Reviews. Cardiology·Rishi PuriJosep Rodés-Cabau
Aug 28, 2017·The Canadian Journal of Cardiology·Chekrallah ChamandiJosep Rodés-Cabau
Dec 12, 2018·Expert Review of Medical Devices·David Del ValJosep Rodés-Cabau

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