Transcatheter closure of patent foramen ovale to prevent stroke recurrence in patients with otherwise unexplained ischaemic stroke: Expert consensus of the French Neurovascular Society and the French Society of Cardiology

Archives of Cardiovascular Diseases
J L MasFabrice Vuillier

Abstract

Unlike previous randomized clinical trials (RCTs), recent trials and meta-analyses have shown that transcatheter closure of patent foramen ovale (PFO) reduces stroke recurrence risk in young and middle-aged adults with an otherwise unexplained PFO-associated ischaemic stroke. To produce an expert consensus on the role of transcatheter PFO closure and antithrombotic drugs for secondary stroke prevention in patients with PFO-associated ischaemic stroke. Five neurologists and five cardiologists with extensive experience in the relevant field were nominated by the French Neurovascular Society and the French Society of Cardiology to make recommendations based on evidence from RCTs and meta-analyses. The experts recommend that any decision concerning treatment of patients with PFO-associated ischaemic stroke should be taken after neurological and cardiological evaluation, bringing together the necessary neurovascular, echocardiography and interventional cardiology expertise. Transcatheter PFO closure is recommended in patients fulfilling all the following criteria: age 16-60 years; recent (≤6 months) ischaemic stroke; PFO associated with atrial septal aneurysm (>10mm) or with a right-to-left shunt>20 microbubbles or with a diameter≥2...Continue Reading

Citations

May 26, 2020·Echocardiography·Christophe BeylsLaurent Leborgne
Feb 28, 2021·Journal of Thrombosis and Thrombolysis·Constantina AggeliKostas Tsioufis
Mar 6, 2021·European Heart Journal Supplements : Journal of the European Society of Cardiology·Iris ParriniRiccardo Asteggiano
Jul 19, 2020·Archives of Cardiovascular Diseases·Noelie MitonClaire Dauphin
May 10, 2020·Journal of the American College of Cardiology·David E Thaler
Jun 19, 2021·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·David J GladstoneAlexandre Y Poppe

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