Transcatheter valve-in-valve implantation (VinV-TAVR) for failed surgical aortic bioprosthetic valves

Clinical Research in Cardiology : Official Journal of the German Cardiac Society
Bernhard WernlyAlexander Lauten

Abstract

We sought to investigate the procedural and hemodynamic outcome after valve-in-valve transcatheter aortic valve replacement (VinV-TAVR) for different surgical (SBV) and transcatheter (TAVR) bioprosthetic valves. 223 patients (76 ± 11years, STS-Score 8.3 ± 10.1) suffering from SBV failure treated with VinV-TAVR were enrolled at 6 centers across Germany. At time of the intervention, the majority of patients were in NYHA-class ≥ III (88%, n = 180). Failure mode of the SBVs was either stenosis, regurgitation (AR) or a combination of both in 85 (38%), 76 (34%) and 62 (28%) patients, respectively. 138 (62%) patients were treated with first generation TAVR valves (Edwards Sapien XT or CoreValve). Second generation valves were implanted in 85 (38%) patients (Sapien 3, Medtronic CoreValve Evolut, SJM-Portico, JenaValve). VinV-TAVR was associated with high procedural success rate, conversion to surgery was necessary in 3 (2%) patients. After VinV-TAVR procedure, 4 (2%) patients suffered from ≥ moderate AR. In 6 (3%) patients a second valve was implanted due to mispositioning of the first valve and subsequent severe paravalvular AR. Coronary obstruction was observed in 4 (2%) patients. Major bleeding and cerebrovascular complications (acc...Continue Reading

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Citations

Mar 10, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Janarthanan SathananthanJohn Webb
Dec 1, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Stephan KrapfChristian Thilo
Jul 4, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Hector A Alvarez-CovarrubiasA Markus Kasel
May 19, 2020·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Ahmed N MahmoudDanny Dvir
Aug 28, 2020·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Michael MorcosAndrew Remppis
Jun 2, 2020·Frontiers in Pharmacology·Brunilda AlushiAlexander Lauten
Jun 26, 2020·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Bruna GomesBenjamin Meder
Nov 25, 2020·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Tsuyoshi YamabeHiroo Takayama
Oct 16, 2020·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Daniela HaaseP Christian Schulze
Mar 3, 2020·JACC. Cardiovascular Interventions·Mark HenseyJohn Webb
May 8, 2021·Journal of the American College of Cardiology·Alberto AlperiDanny Dvir

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