PMID: 2413280Sep 1, 1985

Transcortin and alpha 2u-globulin messenger RNA activities during turpentine-induced inflammation in the rat

Journal of Steroid Biochemistry
D FaictP De Moor

Abstract

Previously we have shown that the serum concentration of transcortin and alpha 2u-globulin markedly decreases during turpentine-induced inflammation. In the present study transcortin and alpha 2u-globulin mRNA from healthy rats and from animals with inflammation was translated in a rabbit reticulocyte lysate system. Female rats had higher levels of translatable transcortin mRNA than male animals and the level of mRNA for transcortin and alpha 2u-globulin decreased rapidly during inflammation. These results indicate that the sex difference in the serum level of transcortin and the changes in serum transcortin and alpha 2u-globulin during inflammation are mainly determined by differences in the mRNAs in the liver.

References

Jan 1, 1991·The Journal of Steroid Biochemistry and Molecular Biology·G L HammondD A Underhill
Jan 22, 1998·The American Journal of Physiology·T DeakS F Maier
Oct 16, 1999·Journal of Neuroendocrinology·N ShanksS L Lightman

Citations

Jan 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·M L MaccecchiniG Schatz
Aug 1, 1976·European Journal of Biochemistry·H R Pelham, R J Jackson
Jun 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·H Aviv, P Leder
Sep 1, 1984·Archives of Biochemistry and Biophysics·K P AndersonE C Heath
Apr 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·P R DobnerF C Bancroft

Related Concepts

Turpentine
Alpha 2u globulin
August Rats
Protein Biosynthesis
Globulins
Reticulocytes
Transcortin
Inflammation
Genomic Hybridization
Alpha-Globulins

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