Transcranial direct current stimulation effects on hand sensibility as measured by an objective quantitative analysis device: a randomized single-blind sham-control crossover clinical trial.

Neuroreport
Hanan Ibrahim ZehryToru Sunagawa

Abstract

Studies show that transcranial direct current stimulation (tDCS) can modulate somatosensory processing, but optimum parameters for tDCS effects on hand sensibility remain in question. We aimed to test the effects of anodal tDCS (atDCS) and cathodal tDCS (ctDCS) compared with sham tDCS (stDCS) of primary motor (M1) and sensory (S1) cortices on healthy subjects' hand sensibility. In this single-blind clinical trial, 30 randomized healthy volunteers received six tDCS sessions over 6 weeks: one session each of atDCS, ctDCS and stDCS over M1, and one session each of atDCS, ctDCS and stDCS over S1. Current perception threshold (CPT) was assessed using an objective quantitative analysis device (PainVision) at baseline, immediately (T0) and 30 min (T30) after each intervention. Our results showed that both atDCS and ctDCS of S1 and M1 significantly increased CPT. M1 ctDCS at T30 had the greatest effect of all M1 and S1 stimulation conditions (mean difference: 32.94%, Z: 3.12, effect size: 1.82, P < 0.001 The largest effect at S1 was for atDCS at T30 (mean difference: 29.87%, Z: 2.53, effect size: 1.72, P < 0.001. Our results are consistent with tDCS' modulatory effects on hand sensation, especially M1 ctDCS and S1 atDCS.

References

Jan 28, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Kaoru MatsunagaJohn C Rothwell
Aug 26, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Anne DieckhöferRené Gobbelé
Aug 23, 2008·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·P S BoggioF Fregni
Oct 1, 2008·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Gabor CsifcsakWalter Paulus
Dec 31, 2009·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Soroush ZaghiFelipe Fregni
Jun 24, 2010·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Cornelius G BachmannSvenja Happe
Jul 1, 2008·Brain Stimulation·Michael A NitscheAlvaro Pascual-Leone
Feb 22, 2014·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·B VaseghiS Jaberzadeh
Apr 18, 2014·Brain : a Journal of Neurology·Yumi MaedaVitaly Napadow
Jul 4, 2015·Attention, Perception & Psychophysics·Thiago L CostaDora F Ventura
Sep 1, 2015·Maxillofacial Plastic and Reconstructive Surgery·Young-Kyun KimWon Lee
Dec 15, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·A J WoodsM A Nitsche
Dec 8, 2017·Frontiers in Neuroscience·Hayley ThairAlastair D Smith

❮ Previous
Next ❯

Software Mentioned

PainVision
PainVision PS - 2100

Related Concepts

Related Feeds

Barrel cortex

Here is the latest research on barrel cortex, a region of somatosensory and motor corticies in the brain, which are used by animals that rely on whiskers for world exploration.