Transcranial Direct Current Stimulation (tDCS) Enhances the Excitability of Trigemino-Facial Reflex Circuits

Brain Stimulation
Christopher CabibJosep Valls-Solé

Abstract

Transcranial direct current stimulation (tDCS) causes a tiny burning sensation through activation of local cutaneous trigeminal afferents. Trigeminal sensory inputs from tDCS may generate excitability changes in the trigemino-facial reflex circuits. Sixteen healthy volunteers were submitted to 20 minutes tDCS sessions with two types of electrode-montage conditions: 1. Real vs Sham 'bi-hemispheric' tDCS (cathode/anode: C4/C3), for blinded assessment of effects, and 2. 'uni-hemispheric' tDCS (cathode/anode: Fp3/C3), for assessment of laterality of the effects. Supraorbital nerve stimuli were used to obtain blink reflexes before, during (10 minutes from onset) and after (30 minutes from onset) the tDCS session. Outcome measures were R2 habituation (R2H) to repeated stimuli, the blink reflex excitability recovery (BRER) to paired stimuli and the blink reflex inhibition by a prepulse (BRIP). Real but not sham bi-hemispheric tDCS caused a significant decrease of R2H and leftward shift of BRER curve (p < 0.05 for all measures). The effects of uni-hemispheric tDCS on BRER and BRIP were larger on ipsilateral than on contralateral blink reflexes (p < 0.05). Excitability changes were still present 10 minutes after the end of stimulation i...Continue Reading

References

Jun 1, 1977·Journal of Comparative and Physiological Psychology·M Davis, P M Gendelman
Dec 1, 1982·Electroencephalography and Clinical Neurophysiology·R DenglerA Struppler
Sep 1, 1983·Journal of Neurology, Neurosurgery, and Psychiatry·A BerardelliM Manfredi
Apr 14, 1999·The Journal of Physiology·J Valls-SoléE Muñoz
Nov 7, 1999·Experimental Brain Research·J Valls-SoléF Nobbe
Jan 4, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·D MancaJ Valls-Solé
Apr 11, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Michael A NitscheWalter Paulus
Sep 1, 1958·Brain : a Journal of Neurology·H G KUYPERS
Feb 24, 2004·The Journal of Physiology·Marom BiksonJohn G R Jefferys
Jul 21, 2004·Journal of Motor Behavior·Anthony N CarlsenIan M Franks
Jul 28, 2005·The European Journal of Neuroscience·Nicolas LangRichard S Frackowiak
Jan 24, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Prateek C GandigaLeonardo G Cohen
Jun 1, 2006·Brain : a Journal of Neurology·João CostaJordi Rumià
Oct 24, 2006·Movement Disorders : Official Journal of the Movement Disorder Society·Stephen TischMarwan Hariz
Jul 16, 2008·Cephalalgia : an International Journal of Headache·A PerrottaG Nappi
Nov 22, 2008·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·A De VitoR Quatrale
Jul 17, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Joseph M GaleaPablo Celnik
Jul 1, 2008·Brain Stimulation·Michael A NitscheAlvaro Pascual-Leone
Oct 20, 2010·The European Journal of Neuroscience·Matteo BolognaAlfredo Berardelli
Mar 13, 2013·The Journal of Physiology·Asif RahmanMarom Bikson
Mar 20, 2013·The Journal of Physiology·Francesco BolzoniElzbieta Jankowska
Jun 19, 2013·The Journal of Physiology·F BolzoniE Jankowska
Feb 13, 2015·Journal of Neurophysiology·Jaime KaminerCraig Evinger

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Citations

Mar 7, 2019·Frontiers in Psychology·Anke Ninija KarabanovHartwig Roman Siebner
Jan 10, 2020·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Marom Bikson, Jacek Dmochowski
Mar 2, 2021·Neural Regeneration Research·Hatice KumruJosep Valls-Sole

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