Transcranial magnetic stimulation in the visual system. I. The psychophysics of visual suppression

Experimental Brain Research
Thomas KammerFelix A Wichmann

Abstract

When applied over the occipital pole, transcranial magnetic stimulation (TMS) disrupts visual perception and induces phosphenes. Both the underlying mechanisms and the brain structures involved are still unclear. The first part of the study characterizes the suppressive effect of TMS by psychophysical methods. Luminance increment thresholds for orientation discrimination were determined in four subjects using an adaptive staircase procedure. Coil position was controlled with a stereotactic positioning device. Threshold values were modulated by TMS, reaching a maximum effect at a stimulus onset asynchrony (SOA) of approx. 100 ms after visual target presentation. Stronger TMS pulses increased the maximum threshold while decreasing the SOA producing the maximum effect. Slopes of the psychometric function were flattened with TMS masking by a factor of 2, compared to control experiments in the absence of TMS. No change in steepness was observed in experiments using a light flash as the mask instead of TMS. Together with the finding that at higher TMS intensities, threshold elevation occurs even with shorter SOAs, this suggests lasting inhibitory processes as masking mechanisms, contradicting the assumption that the phosphene as exci...Continue Reading

References

Jun 1, 1978·Electroencephalography and Clinical Neurophysiology·N Osaka, M Yamamoto
Oct 1, 1992·Journal of Neurophysiology·J H Maunsell, J R Gibson
Aug 1, 1991·Electroencephalography and Clinical Neurophysiology·P FuhrM Hallett
Jan 1, 1990·Psychological Research·P JaśkowskiP Swidzinski
Nov 1, 1989·Electroencephalography and Clinical Neurophysiology·V E AmassianL Eberle
May 11, 1985·Lancet·A T BarkerI L Freeston
Dec 1, 1973·Vision Research·R J Mansfield
Jan 1, 1981·Vision Research·P Lennie
Feb 1, 1995·Brain : a Journal of Neurology·G Beckers, S Zeki
Sep 1, 1995·Vision Research·B Treutwein
Mar 10, 1999·Perception & Psychophysics·B Treutwein, H Strasburger
Apr 23, 1999·Neuroscience Letters·T KammerK Kirschfeld
Sep 24, 1999·Vision Research·L L Kontsevich, C W Tyler
Feb 13, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·T KammerH Topka
Jan 22, 2002·Perception & Psychophysics·F A Wichmann, N J Hill
Jan 22, 2002·Perception & Psychophysics·F A Wichmann, N J Hill

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Citations

Jan 15, 2008·Experimental Brain Research·Tim WagnerAlvaro Pascual-Leone
May 29, 2003·Neuroscience Letters·Thomas KammerMichael H Herzog
May 26, 2009·Cerebral Cortex·A ThielscherK Uludağ
Sep 9, 2005·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Alan Cowey
Dec 7, 2007·Journal of Cognitive Neuroscience·Justin A HarrisCarlo Miniussi
May 6, 2009·Journal of Cognitive Neuroscience·Joan A CamprodonAlvaro Pascual-Leone
Dec 20, 2012·Journal of Cognitive Neuroscience·Silvia ConventoNadia Bolognini
May 15, 2013·Journal of Cognitive Neuroscience·Marjan Persuh, Tony Ro
Apr 3, 2010·Journal of Visualized Experiments : JoVE·Seth Elkin-FrankstonAntoni Valero-Cabr
Jan 1, 2007·Advances in Cognitive Psychology·Thomas Kammer
Sep 19, 2007·The British Journal of Radiology·F de VochtH Kromhout
Jun 9, 2005·Experimental Brain Research·Edward J Tehovnik, Warren M Slocum
Apr 17, 2012·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Christopher D ChambersMark A Williams
Jun 7, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Michael SiniatchkinUlrich Stephani
Mar 23, 2011·Revue neurologique·A Valero-CabréO A Coubard
Feb 22, 2011·Neuroscience Letters·Mihkel StammTalis Bachmann
Jun 19, 2007·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Erik CorthoutAlan Cowey
Nov 26, 2005·The European Journal of Neuroscience·Edward J TehovnikPeter H Schiller
Feb 7, 2012·The European Journal of Neuroscience·Mika KoivistoHenry Railo
Mar 19, 2016·ELife·Sean C MurphyMatthew E Larkum
Sep 1, 2015·Experimental Brain Research·Ramisha KnightSilvia Savazzi
May 7, 2013·Neuropsychologia·Tatiana Aloi EmmanouilTony Ro
Jul 11, 2014·Neuroscience and Biobehavioral Reviews·Tom A de GraafAlexander T Sack
Apr 18, 2009·NeuroImage·A Thielscher, F A Wichmann
Aug 13, 2014·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Christianne JacobsAlexander T Sack
Feb 18, 2015·Frontiers in Behavioral Neuroscience·Tom A de GraafAlexander T Sack
Aug 9, 2016·Neuroscience of Consciousness·Megan A K PetersHakwan Lau
Oct 15, 2009·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Declan J McKeefryAntony B Morland
Mar 19, 2011·Human Brain Mapping·Niina Salminen-VaparantaSimo Vanni
Apr 28, 2006·Psychological Research·Thomas Kammer
Aug 10, 2006·Experimental Brain Research·Edward J Tehovnik, Warren M Slocum
Mar 27, 2019·Journal of Cognitive Neuroscience·Tony Ro
Jul 20, 2007·Journal of Neurophysiology·Robin LaycockSheila G Crewther
Aug 19, 2007·Journal of Neurophysiology·S F W NeggersJ L Kenemans

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