Transcranial Static Magnetic Field Stimulation over the Primary Motor Cortex Induces Plastic Changes in Cortical Nociceptive Processing

Frontiers in Human Neuroscience
Hikari KirimotoAntonio Oliviero

Abstract

Transcranial static magnetic field stimulation (tSMS) is a novel and inexpensive, non-invasive brain stimulation (NIBS) technique. Here, we performed non-invasive modulation of intra-epidermal electrical stimulation-evoked potentials (IES-EPs) by applying tSMS or sham stimulation over the primary motor (M1) and somatosensory (S1) cortices in 18 healthy volunteers for 15 min. We recorded EPs after IES before, right after, and 10 min after tSMS. The IES-EP amplitude was significantly reduced immediately after tSMS over M1, whereas tSMS over S1 and sham stimulation did not affect the IES-EP amplitude. Thus, tSMS may affect cortical nociceptive processing. Although the results of intervention for experimental acute pain in healthy subjects cannot be directly translated into the clinical situation, tSMS may be a potentially useful NIBS method for managing chronic pain, in addition to standard of care treatments.

Associated Clinical Trials

References

May 10, 1976·Experimental Brain Research·A CarmonJ Goldberg
Jan 1, 1991·Pacing and Clinical Electrophysiology : PACE·T TsubokawaS Koyama
Jan 1, 1991·Acta neurochirurgica. Supplementum·T TsubokawaS Koyama
Mar 1, 1989·Electroencephalography and Clinical Neurophysiology·R KakigiA Ikeda
Jun 2, 1995·Neuroscience Letters·R KakigiS Watanabe
Jun 13, 1996·Biochimica Et Biophysica Acta·A D Rosen
Mar 4, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·H KaubeJ Ellrich
Oct 30, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·H EnomotoI Kanazawa
Sep 30, 2003·Cell Biochemistry and Biophysics·Arthur D Rosen
Jan 28, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Kaoru MatsunagaJohn C Rothwell
Jul 28, 2005·The European Journal of Neuroscience·Nicolas LangRichard S Frackowiak
Apr 15, 2006·Cerebral Cortex·Maud FrotLuis Garcia-Larrea
Mar 3, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·William W SeeleyMichael D Greicius
Mar 27, 2007·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Seiko IshikawaJohn C Rothwell
Jun 6, 2008·Journal of Neurophysiology·G D IannettiA Mouraux
Oct 1, 2008·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Gabor CsifcsakWalter Paulus
Jun 19, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Michael C LeeGian Domenico Iannetti
Jan 16, 2010·The Journal of Pain : Official Journal of the American Pain Society·Naofumi OtsuruRyusuke Kakigi
Jan 26, 2010·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Jean-Pascal LefaucheurJean-Paul Nguyen
Jun 1, 2010·Brain Structure & Function·Vinod Menon, Lucina Q Uddin
Nov 3, 2010·Progress in Neurobiology·Valéry LegrainAndré Mouraux
Jan 27, 2011·Journal of Cognitive Neuroscience·Elia ValentiniGian Domenico Iannetti
Aug 3, 2011·The Journal of Physiology·Antonio OlivieroJuan Aguilar
Dec 6, 2011·Journal of Neurology, Neurosurgery, and Psychiatry·Koji Inui, Ryusuke Kakigi
May 29, 2012·Pain·Veit MyliusJean-Pascal Lefaucheur
Oct 9, 2012·Neurophysiologie clinique = Clinical neurophysiology·V LegrainE Valentini
Feb 19, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Shigeki OmoriRyusuke Kakigi

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Citations

Jan 5, 2019·Neuromodulation : Journal of the International Neuromodulation Society·Kento NakagawaKimitaka Nakazawa
Jul 30, 2019·Neuromodulation : Journal of the International Neuromodulation Society·Kai HeimrathTino Zaehle
Aug 2, 2018·Current Opinion in Supportive and Palliative Care·Roberto CasaleGiovanni Taveggia
Nov 28, 2020·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Simone RossiUNKNOWN basis of this article began with a Consensus Statement from the IFCN Workshop on "Present, Future of TMS: Safety, Ethical Gu
Mar 7, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Nuria Viudes-SarrionCarmen Lillo-Navarro

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