Transcranial Stimulation of the Dorsolateral Prefrontal Cortex Prevents Stress-Induced Working Memory Deficits

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Mario Bogdanov, Lars Schwabe

Abstract

Stress is known to impair working memory performance. This disruptive effect of stress on working memory has been linked to a decrease in the activity of the dorsolateral prefrontal cortex (dlPFC). In the present experiment, we tested whether transcranial direct current stimulation (tDCS) of the dlPFC can prevent stress-induced working memory impairments. We tested 120 healthy participants in a 2 d, sham-controlled, double-blind between-subjects design. Participants completed a test of their individual baseline working memory capacity on day 1. On day 2, participants were exposed to either a stressor or a control manipulation before they performed a visuospatial and a verbal working memory task. While participants completed the tasks, anodal, cathodal, or sham tDCS was applied over the right dlPFC. Stress impaired working memory performance in both tasks, albeit to a lesser extent in the verbal compared with the visuospatial working memory task. This stress-induced working memory impairment was prevented by anodal, but not sham or cathodal, stimulation of the dlPFC. Compared with sham or cathodal stimulation, anodal tDCS led to significantly better working memory performance in both tasks after stress. Our findings indicate a c...Continue Reading

Citations

Nov 20, 2016·The European Journal of Neuroscience·Lars Schwabe
Jun 20, 2017·Memory·Conny W E M Quaedflieg, Lars Schwabe
Feb 16, 2019·Stress : the International Journal on the Biology of Stress·Grant S ShieldsAndrew P Yonelinas
Apr 27, 2019·Stress : the International Journal on the Biology of Stress·Xuewei WangWeiping Hu
Jan 4, 2020·Cognitive, Affective & Behavioral Neuroscience·Yael L E AnkriOded Meiron
Sep 24, 2016·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Zaira CattaneoCostanza Papagno
Jan 30, 2020·Social Cognitive and Affective Neuroscience·Fenne M SmitsElbert Geuze
Apr 27, 2020·The British Journal of Surgery·R PatelD R Leff
Jun 26, 2020·Psychopharmacology·Nadine WankeLars Schwabe
Jul 31, 2020·Experimental Psychology·Petra LuersJens C Prüssner
Aug 21, 2020·Cerebral Cortex·Stefan Schulreich, Lars Schwabe
Feb 13, 2018·Cognitive Neurodynamics·Ahmad Rauf SubhaniAamir Saeed Malik
Sep 25, 2017·Frontiers in Human Neuroscience·Wei LiuBing Jin Li
Jan 13, 2021·Journal of Psychiatric Research·Jerome Brunelin, Shirley Fecteau
Apr 27, 2021·Brain, Behavior, & Immunity Health·Grant S ShieldsCamelia E Hostinar
Jun 4, 2021·Frontiers in Human Neuroscience·Ingo HertrichHermann Ackermann
Sep 1, 2021·Psychological Science·Mario BogdanovA Ross Otto
Nov 6, 2021·Human Brain Mapping·Mickaël CausseFlorence Rémy
Nov 9, 2021·Neuroscience and Biobehavioral Reviews·Elizabeth McManusNils Muhlert
Nov 23, 2021·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Yifan WangHaijun Duan

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