Transcription factors in the pathogenesis of autoimmunity

Jan 27, 1998·European Journal of Immunogenetics : Official Journal of the British Society for Histocompatibility and Immunogenetics·J JohannesenF Pociot

Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B

Apr 16, 1998·The Journal of Clinical Investigation·C WahlR M Schmid

T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon gamma expression by T cells

May 23, 1998·The Journal of Experimental Medicine·S J SimpsonC Terhorst

Transcriptional regulation during B cell development

May 23, 1998·Annual Review of Immunology·A Henderson, K Calame

Jaks and STATs: biological implications

May 23, 1998·Annual Review of Immunology·W J Leonard, J J O'Shea

Transcription factor NF-kappaB and inhibitor I kappaBalpha are localized in macrophages in active multiple sclerosis lesions

May 26, 1998·Journal of Neuropathology and Experimental Neurology·D GvericJ Newcombe

Autoimmune diabetes: the role of T cells, MHC molecules and autoantigens

Jun 3, 1998·Autoimmunity·I Durinovic-Belló

Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa

Jul 25, 1998·Gastroenterology·G RoglerV Gross

Mediation by NF-kappa B of cytokine induced expression of intercellular adhesion molecule 1 (ICAM-1) in an intestinal epithelial cell line, a process blocked by proteasome inhibitors

Aug 6, 1998·Gut·C JobinR B Sartor

Aiolos regulates B cell activation and maturation to effector state

Nov 7, 1998·Immunity·J H WangK Georgopoulos

NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint

Nov 13, 1998·Proceedings of the National Academy of Sciences of the United States of America·A V MiagkovS S Makarov

Activation of nuclear factor kappa B in Crohn's disease

Dec 29, 1998·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·R D EllisN A Punchard

AP-1 and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis

Jan 19, 1999·Autoimmunity·Z HanG S Firestein

Cytokine gene transcription by NF-kappa B family members in patients with inflammatory bowel disease

Feb 3, 1999·Annals of the New York Academy of Sciences·M F NeurathK H Büschenfelde

T-box genes: what they do and how they do it

Apr 28, 1999·Trends in Genetics : TIG·J Smith

Mechanisms of central and peripheral T-cell tolerance: lessons from experimental models of multiple sclerosis

Aug 18, 1999·Immunological Reviews·S AndertonD Wraith

Autoreactive CD4+ T cells protect from autoimmune diabetes via bystander suppression using the IL-4/Stat6 pathway

Nov 5, 1999·Immunity·D HomannM G von Herrath

Activation of NF-kappaB and c-jun transcription factors in multiple sclerosis lesions. Implications for oligodendrocyte pathology

Nov 7, 1999·The American Journal of Pathology·B BonettiC S Raine

Detection of interferon regulatory factor-1 in lamina propria mononuclear cells in Crohn's disease

Jan 12, 2000·Journal of Pediatric Gastroenterology and Nutrition·M ClavellE Mannick

Differentiated dendritic cells expressing nuclear RelB are predominantly located in rheumatoid synovial tissue perivascular mononuclear cell aggregates

Apr 15, 2000·Arthritis and Rheumatism·A R PettitR Thomas

Activation of nuclear factor-kB in the spinal cord of experimental allergic encephalomyelitis

Jun 8, 2000·Neuroscience Letters·K Pahan, M Schmid

Macrophage-derived cytokine and nuclear factor kappaB p65 expression in synovial membrane and skin of patients with psoriatic arthritis

Jun 17, 2000·Arthritis and Rheumatism·C L DanningI B McInnes

Distinct roles for the NF-kappaB1 (p50) and c-Rel transcription factors in inflammatory arthritis

Jun 23, 2000·The Journal of Clinical Investigation·I K CampbellI P Wicks

Butyrate inhibits inflammatory responses through NFkappaB inhibition: implications for Crohn's disease

Aug 15, 2000·Gut·J P SegainJ P Galmiche

Orchestrated response: a symphony of transcription factors for gene control

Oct 21, 2000·Genes & Development·B Lemon, R Tjian

JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome

Dec 20, 2000·The Journal of Clinical Investigation·T A ChatilaA M Bowcock

Variable effects of transgenic c-Maf on autoimmune diabetes

Jan 9, 2001·Diabetes·M E PauzaD Lo

Expression and function of Ets transcription factors in mammalian development: a regulatory network

Feb 15, 2001·Oncogene·I G Maroulakou, D B Bowe

CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation

Feb 22, 2001·The Journal of Experimental Medicine·A SuzukiA Yoshimura

Lack of association between the interferon regulatory factor-1 (IRF1) locus at 5q31.1 and multiple sclerosis in Germany, northern Italy, Sardinia and Sweden

Feb 24, 2001·Genes and Immunity·K VandenbroeckG Opdenakker

STAT expression and localization in the central nervous system during autoimmune encephalomyelitis in Lewis rats

Mar 10, 2001·Journal of Neuroimmunology·Y JeeY Matsumoto

Cytokine pathways and joint inflammation in rheumatoid arthritis

Mar 22, 2001·The New England Journal of Medicine·E H Choy, G S Panayi

Partners in transcription: NFAT and AP-1

Jun 13, 2001·Oncogene·F MaciánA Rao

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Citations

Hemolysate-induced expression of intercellular adhesion molecule-1 and monocyte chemoattractant protein-1 expression in cultured brain microvascular endothelial cells via through ROS-dependent NF-kappaB pathways.

Aug 30, 2008·Cellular and Molecular Neurobiology·Hua LuHong-Xia Yin

Mechanisms of disease: Transcription factors in inflammatory arthritis

Aug 26, 2006·Nature Clinical Practice. Rheumatology·Dee Aud, Stanford L Peng

Interplay between the NF-kappaB and forkhead transcription factors

Apr 30, 2005·Cell Death and Differentiation·S L Peng

Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM

Mar 13, 2014·Human Molecular Genetics·Amit K MaitiSwapan K Nath

Liver-X-receptor activator prevents homocysteine-induced production of IgG antibodies from murine B lymphocytes via the ROS-NF-kappaB pathway.

Apr 21, 2007·Biochemical and Biophysical Research Communications·Lina ChangXian Wang

Differential expression of SOCS1 in macrophages in relapsing-remitting and chronic EAE and its role in disease severity

Jul 21, 2010·Glia·Jennifer L BerardSamuel David

Oncogenic and metastatic properties of preprotachykinin-I and neurokinin-1 genes

Aug 12, 2006·Vascular Pharmacology·Arun S SinghPranela Rameshwar

NK-1 receptor antagonists as antitumor drugs: a survey of the literature from 2000 to 2011

Jun 16, 2012·Expert Opinion on Therapeutic Patents·Miguel MuñozRafael Coveñas

Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a

Aug 17, 2004·Immunity·Ling LinStanford L Peng

B cell response is required for granuloma formation in the early infection of Schistosoma japonicum.

Mar 6, 2008·PloS One·Fang JiJian Sun

Interactions of Fox proteins with inflammatory transcription-factor pathways

Nov 1, 2006·Expert Review of Clinical Immunology·Stanford L Peng

Targeting NK-1 Receptors to Prevent and Treat Pancreatic Cancer: a New Therapeutic Approach

Jul 15, 2015·Cancers·Miguel Muñoz, Rafael Coveñas

Basic Science for the clinician 41: tails of cytokine receptor activation and control: JAKs, STATs, PIASs, and SOCSs

Dec 7, 2006·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Leonard H Sigal

Interferon regulatory factor-1 gene deletion decreases glomerulonephritis in MRL/lpr mice

Mar 17, 2006·European Journal of Immunology·Christopher M ReillyGary S Gilkeson

New insights into the pathogenesis of inflammatory bowel disease: transcription factors analysis in bioptic tissues from pediatric patients

Feb 22, 2011·Journal of Pediatric Gastroenterology and Nutrition·Maria PierdomenicoAnna Negroni

Rheumatoid arthritis is associated with IgG antibodies to human endogenous retrovirus gag matrix: a potential pathogenic mechanism of disease?

Sep 17, 2014·The Journal of Rheumatology·Paul N NelsonPaul B Rylance

The role of molecular mimicry and other factors in the association of Human Endogenous Retroviruses and autoimmunity

Jan 29, 2016·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Malgorzata TrelaPaul B Rylance

The substance P/NK-1 receptor system: NK-1 receptor antagonists as anti-cancer drugs

May 13, 2015·Journal of Biosciences·Miguel MunozMaximino Redondo

Restraint of B cell activation by Foxj1-mediated antagonism of NF-kappa B and IL-6

Jul 9, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Ling LinStanford L Peng

Coordination of NF-kappaB and NFAT antagonism by the forkhead transcription factor Foxd1

Apr 6, 2006·The Journal of Immunology : Official Journal of the American Association of Immunologists·Ling Lin, Stanford L Peng

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Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.