PMID: 2106510Mar 1, 1990Paper

Transcription of the ftsZ gene and cell division in Escherichia coli

Journal of Bacteriology
A RobinR D'Ari

Abstract

The ftsZ gene of Escherichia coli, which lies in a cluster of cell division genes at 2 min on the genetic map, codes for a protein which is thought to play a key role in triggering cell division. Using an ftsZ::lacZ operon fusion, we have studied the transcription of the ftsZ gene under conditions in which cell division was either inhibited or synchronized in the bacterial population. In ftsZ, ftsA, ftsQ, and ftsI (or pbpB) mutants, there was no change in the differential rate of expression of the ftsZ gene in nonpermissive conditions, when cell division was completely blocked. Although the FtsZ protein is thought to be limiting for cell division, in synchronized cultures the ftsZ gene was expressed not only at the moment of septation initiation but throughout the cell cycle. Its expression, however, was not exponential but linear, with a rapid doubling in rate at a specific cell age; this age, about 20 min after division in a 60-min cycle, was different from the age at which the ftsZ::lacZ operon was duplicated. However, it was close to the age at which replication initiated and at which the rate of phospholipid synthesis doubled. During the transient division inhibition after a nutritional shift-up, ftsZ transcription again b...Continue Reading

References

Oct 1, 1989·Molecular Microbiology·S J DewarW D Donachie
Sep 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·C Jones, I B Holland
Aug 5, 1985·Journal of Molecular Biology·Q M YiJ Lutkenhaus
Oct 1, 1985·Cell·J E Ward, J Lutkenhaus
Aug 1, 1985·Journal of Bacteriology·K J Begg, W D Donachie
Sep 1, 1974·Journal of Bacteriology·F C NeidhardtD F Smith
Jul 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·O HuismanS Gottesman
Jun 1, 1984·Journal of Bacteriology·N F Sullivan, W D Donachie
Jun 1, 1983·Journal of Bacteriology·J F Lutkenhaus
Mar 15, 1984·European Journal of Biochemistry·D Joseleau-PetitA Kepes
Oct 1, 1981·Journal of Bacteriology·S GottesmanP Trisler
Dec 1, 1958·Journal of General Microbiology·N O KJELDGAARDM SCHAECHTER

❮ Previous
Next ❯

Citations

Jan 1, 1992·Archives of Microbiology·A WitteW Lubitz
Dec 6, 2011·PLoS Neglected Tropical Diseases·Zhiru LiClotilde K Carlow
Sep 2, 1998·Molecular Microbiology·F NavarroD Joseleau-Petit
Mar 28, 2008·Molecular Microbiology·Sean P KennedyFrançois-Xavier Barre
Jun 1, 2000·FEMS Microbiology Letters·S J Dewar, R Dorazi
Sep 20, 2018·Molecular Microbiology·Jaana MännikJaan Männik
Feb 26, 2000·Annual Review of Genetics·L RothfieldJ García-Lara
Jan 24, 2006·Infection and Immunity·Helmy RachmanStefan H E Kaufmann
Dec 29, 1998·Journal of Bacteriology·D Joseleau-PetitR D'Ari
May 1, 1993·Journal of Bacteriology·R W SmithW D Donachie
Oct 1, 1994·Journal of Bacteriology·P Zhou, C E Helmstetter
Jun 1, 1991·Journal of Bacteriology·K Dai, J Lutkenhaus
Apr 1, 1992·Current Opinion in Cell Biology·A Newton, N Ohta
Oct 1, 1993·Current Opinion in Genetics & Development·S Hiraga
Oct 1, 2021·Frontiers in Microbiology·Carlos Martínez-TorróOscar Q Pich

❮ Previous
Next ❯

Related Concepts

Related Feeds