Transcriptional regulation of myeloid-derived suppressor cells

Journal of Leukocyte Biology
Thomas CondamineDmitry I Gabrilovich

Abstract

Myeloid-derived suppressor cells are a heterogeneous group of pathologically activated immature cells that play a major role in the negative regulation of the immune response in cancer, autoimmunity, many chronic infections, and inflammatory conditions, as well as in the regulation of tumor angiogenesis, tumor cell invasion, and metastases. Accumulation of myeloid-derived suppressor cells is governed by a network of transcriptional regulators that could be combined into 2 partially overlapping groups: factors promoting myelopoiesis and preventing differentiation of mature myeloid cells and factors promoting pathologic activation of myeloid-derived suppressor cells. In this review, we discuss the specific nature of these factors and their impact on myeloid-derived suppressor cell development.

References

May 15, 2002·The Biochemical Journal·Dipak P Ramji, Pelagia Foka
Dec 24, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Vincenzo BrontePaola Zanovello
Dec 23, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Yulia NefedovaDmitry Gabrilovich
Jan 7, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Pratima SinhaSuzanne Ostrand-Rosenberg
Apr 2, 2005·Nature Reviews. Molecular Cell Biology·Martin Holcik, Nahum Sonenberg
Apr 9, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Sergei Kusmartsev, Dmitry I Gabrilovich
Sep 28, 2005·The Journal of Experimental Medicine·Paulo C RodriguezAugusto C Ochoa
Oct 4, 2006·The Journal of Clinical Investigation·Giovanna GallinaVincenzo Bronte
Jan 11, 2007·Cancer Research·Dmitry I GabrilovichHans Schreiber
May 8, 2007·Cancer Research·Pratima SinhaSuzanne Ostrand-Rosenberg
Jun 15, 2007·Nature Reviews. Molecular Cell Biology·David Ron, Peter Walter
Feb 6, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Mitsugu FujitaHideho Okada
Jul 25, 2008·Nature Reviews. Cancer·Deborah L Burkhart, Julien Sage
Jul 25, 2008·Nature·Kezhong Zhang, Randal J Kaufman
Oct 4, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Je-In YounDmitry I Gabrilovich
Dec 26, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Hequan LiXuetao Cao
Feb 7, 2009·Nature Reviews. Immunology·Dmitry I Gabrilovich, Srinivas Nagaraj
Mar 6, 2009·Journal of Leukocyte Biology·Stephanie K BuntSuzanne Ostrand-Rosenberg
Apr 14, 2009·International Immunopharmacology·Moses K DonkorJames E Talmadge
Apr 22, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Cesar A CorzoDmitry I Gabrilovich
Jun 23, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Trina J StewartScott I Abrams
Nov 27, 2009·European Journal of Immunology·Luigi DolcettiVincenzo Bronte
Jan 6, 2010·Cancer Immunology, Immunotherapy : CII·David SavitskyTadatsugu Taniguchi
Mar 4, 2010·Journal of Cellular and Molecular Medicine·Trina J StewartScott I Abrams
Mar 30, 2010·The American Journal of Pathology·Yuelong LiuHuang-Ge Zhang
Jul 21, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Melissa G LechnerAlan L Epstein
Jul 28, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Ling ZengJudith A Smith
Aug 31, 2010·The American Journal of Pathology·Xiaoyu XiangHuang-Ge Zhang
Sep 30, 2010·Proceedings of the National Academy of Sciences of the United States of America·Jane C GoodallJ S Hill Gaston

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Citations

Feb 10, 2016·Trends in Immunology·Vinit KumarDmitry I Gabrilovich
Apr 12, 2016·Frontiers in Cellular and Infection Microbiology·Michael OstDominik Hartl
May 30, 2016·Cellular and Molecular Life Sciences : CMLS·Christopher ShippGraham Pawelec
Jul 6, 2016·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Scott I AbramsMichelle N Messmer
Feb 15, 2017·Endocrine-related Cancer·Andrew M K LawDavid Gallego-Ortega
Jan 10, 2018·The Journal of Immunology : Official Journal of the American Association of Immunologists·Suzanne Ostrand-Rosenberg, Catherine Fenselau
Mar 31, 2017·The Journal of Immunology : Official Journal of the American Association of Immunologists·Colleen S NetherbyScott I Abrams
Jun 7, 2017·The Journal of Immunology : Official Journal of the American Association of Immunologists·Anna K BirdJennifer H Anolik
Apr 12, 2017·The Journal of Immunology : Official Journal of the American Association of Immunologists·Serena ZilioPaolo Serafini
Jul 1, 2017·Journal of Cellular Physiology·Elham SafarzadehBehzad Baradaran
May 18, 2018·The Journal of Clinical Investigation·Chong WuLimin Zheng
Sep 28, 2018·The Journal of Clinical Investigation·Veronica HuberLicia Rivoltini
Oct 31, 2018·Virchows Archiv : an International Journal of Pathology·Alessandra TuccittoViviana Vallacchi
Mar 23, 2019·Blood·Morgan A GieseAnna Huttenlocher
Oct 31, 2019·The Journal of Experimental Medicine·Dehong YanXiaochun Wan
Aug 21, 2019·The Journal of Immunology : Official Journal of the American Association of Immunologists·Asha Jayakumar, Alfred L M Bothwell
Nov 9, 2019·Artificial Cells, Nanomedicine, and Biotechnology·Misagh RajabinejadAlireza Rezaiemanesh
Jun 2, 2017·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Zi-Ning ZhangHong Shang
Mar 4, 2020·Cells·Andrew M K LawDavid Gallego-Ortega
Oct 1, 2016·Oncotarget·Camilla Rydberg MillrudKarin Leandersson
Sep 3, 2020·Frontiers of Medicine·Mahmoud Mohammad YaseenAmmar Daoud
Sep 18, 2020·Pigment Cell & Melanoma Research·Grace H AttrillRichard A Scolyer
Oct 16, 2019·Cellular & Molecular Immunology·Kyohei Nakamura, Mark J Smyth
Jun 26, 2020·Frontiers in Immunology·Chong WuLimin Zheng
Feb 23, 2017·Cancer Immunology, Immunotherapy : CII·Colleen S Netherby, Scott I Abrams
May 27, 2017·Journal of Leukocyte Biology·Jason A ChesneyKavitha Yaddanapudi
Jan 20, 2018·Nature Immunology·Filippo VegliaDmitry Gabrilovich
Aug 1, 2018·Frontiers in Immunology·Mahnaz JanghorbanXiang H-F Zhang
Oct 24, 2018·Frontiers in Immunology·Emile J ClappaertDamya Laoui
Aug 17, 2019·Frontiers in Immunology·Wenxin WangShengjun Wang
Aug 14, 2019·Frontiers in Immunology·Gabriela Leija MontoyaNicolás Serafín Higuera

❮ Previous
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