Transcriptional regulation of strigolactone signalling in Arabidopsis.

Nature
Lei WangJiayang Li

Abstract

Plant hormones known as strigolactones control plant development and interactions between host plants and symbiotic fungi or parasitic weeds1-4. In Arabidopsis thaliana and rice, the proteins DWARF14 (D14), MORE AXILLARY GROWTH 2 (MAX2), SUPPRESSOR OF MAX2-LIKE 6, 7 and 8 (SMXL6, SMXL7 and SMXL8) and their orthologues form a complex upon strigolactone perception and play a central part in strigolactone signalling5-10. However, whether and how strigolactones activate downstream transcription remains largely unknown. Here we use a synthetic strigolactone to identify 401 strigolactone-responsive genes in Arabidopsis, and show that these plant hormones regulate shoot branching, leaf shape and anthocyanin accumulation mainly through transcriptional activation of the BRANCHED 1, TCP DOMAIN PROTEIN 1 and PRODUCTION OF ANTHOCYANIN PIGMENT 1 genes. We find that SMXL6 targets 729 genes in the Arabidopsis genome and represses the transcription of SMXL6, SMXL7 and SMXL8 by binding directly to their promoters, showing that SMXL6 serves as an autoregulated transcription factor to maintain the homeostasis of strigolactone signalling. These findings reveal an unanticipated mechanism through which a transcriptional repressor of hormone signalli...Continue Reading

References

Nov 27, 2007·The Plant Journal : for Cell and Molecular Biology·Antonio GonzalezAlan M Lloyd
Aug 12, 2008·Nature·Mikihisa UmeharaShinjiro Yamaguchi
Aug 12, 2008·Nature·Victoria Gomez-RoldanSoizic F Rochange
May 20, 2009·Bioinformatics·Heng Li, Richard Durbin
Jun 10, 2009·Bioinformatics·Heng LiUNKNOWN 1000 Genome Project Data Processing Subgroup
Nov 10, 2009·Bioscience, Biotechnology, and Biochemistry·Kiyoshi MashiguchiTadao Asami
Mar 31, 2010·Proceedings of the National Academy of Sciences of the United States of America·David C NelsonSteven M Smith
Oct 29, 2010·Genome Biology·Simon Anders, Wolfgang Huber
Nov 15, 2011·Nucleic Acids Research·Minoru KanehisaMao Tanabe
Oct 30, 2012·Bioinformatics·Alexander DobinThomas R Gingeras
Nov 15, 2012·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Jihong FuCunyu Yan
May 2, 2013·Nucleic Acids Research·Xin YiZhen Su
Dec 18, 2013·Nature·Liang JiangJiayang Li
Jan 27, 2015·Annual Review of Plant Biology·Salim Al-Babili, Harro J Bouwmeester
Aug 5, 2015·Proceedings of the National Academy of Sciences of the United States of America·M Nagaraj KumarPaul E Verslues
Aug 2, 2016·Nature·Ruifeng YaoDaoxin Xie
Aug 2, 2016·Nature Chemical Biology·Alexandre de Saint GermainFrançois-Didier Boyer
Nov 2, 2016·Biology Open·Tom BennettOttoline Leyser
Nov 17, 2016·Science Advances·Sophia L SamodelovMatias D Zurbriggen
Dec 29, 2016·Proceedings of the National Academy of Sciences of the United States of America·Eduardo González-GrandíoPilar Cubas
Jan 27, 2017·Annual Review of Plant Biology·Mark T WatersDavid C Nelson
Oct 5, 2017·The Plant Journal : for Cell and Molecular Biology·Ourania LantzouniClaus Schwechheimer
Mar 20, 2018·Annual Review of Plant Biology·Bing WangJiayang Li
Jun 27, 2019·Proceedings of the National Academy of Sciences of the United States of America·Jingbo DuanJiayang Li
Aug 30, 2019·PLoS Genetics·José Antonio Villaécija-AguilarCaroline Gutjahr

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Citations

Oct 13, 2020·Frontiers in Plant Science·Marc BehrMarie Baucher
Nov 21, 2020·The Plant Journal : for Cell and Molecular Biology·Bruno AquinoShelley Lumba
Dec 17, 2020·Journal of Integrative Plant Biology·Nai-Qian Dong, Hong-Xuan Lin
Sep 4, 2020·Science China. Life Sciences·Baoyuan QuYang Bai
Jan 26, 2021·Frontiers in Plant Science·Tao YaoJin-Gui Chen
Feb 25, 2021·Trends in Plant Science·Stéphanie M Swarbreck
Feb 7, 2021·The Plant Journal : for Cell and Molecular Biology·Huwei SunQuanzhi Zhao
Apr 4, 2021·International Journal of Molecular Sciences·Zaira M López-JuárezPlinio Guzmán
Apr 2, 2021·Plant Physiology·David C Nelson
Apr 18, 2021·The New Phytologist·Amy M LaFountain, Yao-Wu Yuan
Apr 29, 2021·The New Phytologist·Alastair Robert PlantBarry Causier
Jun 25, 2021·Current Opinion in Plant Biology·Michael BunsickShelley Lumba
Jul 2, 2021·Current Opinion in Plant Biology·Kaori Yoneyama, Philip B Brewer
Jul 11, 2021·The Plant Journal : for Cell and Molecular Biology·Stephanie C KerrCatherine Rameau
Sep 4, 2021·Journal of Agricultural and Food Chemistry·Da-Wei WangZhen Xi
Aug 11, 2020·Molecular Plant·Rongxin ShenHaiyang Wang
Feb 23, 2021·Plant Physiology·Zhiwei LuoKimberley C Snowden

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Methods Mentioned

BETA
ubiquitination
RNA-seq
immunoprecipitation
transgenic
electrophoretic mobility shift
PCR
ChIP
DNA-seq
electrophoresis
genotyping

Software Mentioned

Excel
DESeq
BWA
STAR
ImageJ
MACS
R
FeatureCounts
SAMtools
PlantGSEA

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