Transcriptome wide analyses reveal a sustained cellular stress response in the gill tissue of Trematomus bernacchii after acclimation to multiple stressors

BMC Genomics
Troy J Huth, Sean P Place

Abstract

As global climate change progresses, the Southern Ocean surrounding Antarctica is poised to undergo potentially rapid and substantial changes in temperature and pCO2. To survive in this challenging environment, the highly cold adapted endemic fauna of these waters must demonstrate sufficient plasticity to accommodate these changing conditions or face inexorable decline. Previous studies of notothenioids have focused upon the short-term response to heat stress; and more recently the longer-term physiological response to the combined stress of increasing temperatures and pCO2. This inquiry explores the transcriptomic response of Trematomus bernacchii to increased temperatures and pCO2 at 7, 28 and 56 days, in an attempt to discern the innate plasticity of T. bernacchii available to cope with a changing Southern Ocean. Differential gene expression analysis supported previous research in that T. bernacchii exhibits no inducible heat shock response to stress conditions. However, T. bernacchii did demonstrate a strong stress response to the multi-stressor condition in the form of metabolic shifts, DNA damage repair, immune system processes, and activation of apoptotic pathways combined with negative regulation of cell proliferation. ...Continue Reading

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Citations

May 18, 2016·BMC Genomics·Martha BrownJoseph A Jackson
Jan 21, 2017·The Journal of Experimental Biology·Susana PallarésJosefa Velasco
Nov 7, 2019·BMC Evolutionary Biology·Samuel N Bogan, Sean P Place
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May 17, 2021·Marine Biotechnology·Le WangGen Hua Yue

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Datasets Mentioned

BETA
PRJNA289753

Methods Mentioned

BETA
RNA-seq
GTPase
ubiquitination
environmental stress
protein folding

Software Mentioned

Trinity
Trinity Assembly
Trimmomatic
XSEDE
RNA by Expectation - Maximization ( RSEM ”
EST
Blast
ncbi
RSEM
XSEDE Blacklight

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