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Transcriptome-wide association studies accounting for colocalization using Egger regression

bioRxiv

Nov 21, 2017

Richard BarfieldPeter Kraft

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Abstract

Integrating genome-wide association (GWAS) and expression quantitative trait locus (eQTL) data into transcriptome-wide association studies (TWAS) based on predicted expression can boost power to detect novel disease loci or pinpoint the susceptibility gene at a known disease locus. Howe...read more

Mentioned in this Paper

Genome-Wide Association Study
Study
Quantitative Trait Loci
Mendelian Randomization Analysis
Lipid Droplet
Cancer-Predisposing Gene
Genome
Genes
Advice
Dysequilibrium Syndrome
63
13
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Transcriptome-wide association studies accounting for colocalization using Egger regression

bioRxiv

Nov 21, 2017

Richard BarfieldPeter Kraft

PMID: 990223263

DOI: 10.1101/223263

Abstract

Integrating genome-wide association (GWAS) and expression quantitative trait locus (eQTL) data into transcriptome-wide association studies (TWAS) based on predicted expression can boost power to detect novel disease loci or pinpoint the susceptibility gene at a known disease locus. Howe...read more

Mentioned in this Paper

Genome-Wide Association Study
Study
Quantitative Trait Loci
Mendelian Randomization Analysis
Lipid Droplet
Cancer-Predisposing Gene
Genome
Genes
Advice
Dysequilibrium Syndrome
63
13

Feeds With Similar Papers

Lipid Droplet Biology

Lipid droplets are cellular organelles that store neutral lipids enclosed in a phospholipid monolayer. They are at the centre of lipid and energy homeostasis, and several metabolic diseases including obesity and diabetes. Here is the latest research on lipid droplet biology.

Hormone-Related Cancers

This feed focuses on hormone-related cancers including cancer of the breast, endometrium, ovary, prostate, testis, thyroid, and bone, all of which share unique mechanisms of carcinogenesis. Here is the latest research.

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Paper Details
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  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
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