Transcriptomic analysis reveals protein homeostasis breakdown in the coral Acropora millepora during hypo-saline stress

BMC Genomics
Catalina AguilarDavid J Miller

Abstract

Coral reefs can experience salinity fluctuations due to rainfall and runoff; these events can have major impacts on the corals and lead to bleaching and mortality. On the Great Barrier Reef (GBR), low salinity events, which occur during summer seasons and can involve salinity dropping ~ 10 PSU correlate with declines in coral cover, and these events are predicted to increase in frequency and severity under future climate change scenarios. In other marine invertebrates, exposure to low salinity causes increased expression of genes involved in proteolysis, responses to oxidative stress, and membrane transport, but the effects that changes in salinity have on corals have so far received only limited attention. To better understand the coral response to hypo-osmotic stress, here we investigated the transcriptomic response of the coral Acropora millepora in both adult and juvenile life stages to acute (1 h) and more prolonged (24 h) exposure to low salinity. Differential gene expression analysis revealed the involvement of both common and specific response mechanisms in Acropora. The general response to environmental stressors included up-regulation of genes involved in the mitigation of macromolecular and oxidative damage, while up...Continue Reading

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Datasets Mentioned

BETA
GSE96916

Methods Mentioned

BETA
scraping
RNAseq
protein folding
glycosylation

Software Mentioned

Cytoscape
arrayQualityMetrics
count
TopHat2
htseq
R
DESeq2
BiNGO
R Core Team

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