PMID: 1437353Oct 1, 1992Paper

Transcutaneous blood gas monitoring during salbutamol inhalations in young children with acute asthmatic symptoms

Pediatric Pulmonology
D HolmgrenG Wennergren

Abstract

The effect of salbutamol inhalations on transcutaneous blood gases was investigated in 23 children (aged 11 months-2.5 years) with asthmatic symptoms. After one salbutamol inhalation there was a mean increase in transcutaneous PO2 (tcPO2) of 0.5 kPa (P less than 0.01); after a second dose given 30 minutes later, the mean increase was 1.2 kPa (P less than 0.001). The increase in tcPO2 after only one dose of salbutamol was significantly correlated to age (P less than 0.01). No such correlation was observed after a second dose. The overall increase in tcPO2 after two salbutamol inhalations showed a negative correlation to the duration of the current symptomatic period (P less than 0.05). We conclude that salbutamol inhalations have beneficial effects in young children with acute asthmatic symptoms, even below the age of 18 months, provided that an adequate dose reaches the lung and preferably at an early stage of obstruction.

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Citations

Aug 20, 2015·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·D H ShimJ M Lee
Jan 1, 2012·Scientifica·Wim M van Aalderen
Jul 26, 2002·The Cochrane Database of Systematic Reviews·R ChavasseM McKean

Related Concepts

Acute Disease
Inhalation of Drugs
Sultanol
Asthma
Transcutaneous Partial Pressure of Carbon Dioxide Result
Carbon Dioxide
Dioxygen
Respiration

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