PMID: 9659646Jul 11, 1998Paper

Transcutaneous measurement of carbon dioxide tension during long-distance transport of neonates receiving mechanical ventilation

Journal of Perinatology : Official Journal of the California Perinatal Association
T A O'Connor, R Grueber

Abstract

To determine the efficacy of transcutaneous carbon dioxide tension measurement during high-risk neonatal transport. This was a prospective, randomized comparative study. Infants transported from hospitals more than 30 miles away from our center and who required respiratory intervention were enrolled. Alternating transports used a transcutaneous CO2/O2 monitor. Ventilation parameters and end transport blood gas values served as primary endpoints for the study. Infants with transcutaneous carbon dioxide tension monitoring were more likely to have decreased ventilator peak pressures during transport than neonates not monitored (-1.5 cm H2O vs + 0.6 cm H2O; p = 0.04). Monitored neonates were more likely to arrive at the tertiary center with a more normal pH and a CO2 tension between 35 and 45 mm Hg (4.7 to 6.0 kPa) than nonmonitored infants (p = 0.03 and p = 0.01, respectively). The stabilization times before transport were not significantly prolonged by the use of the transcutaneous monitor. Transcutaneous monitoring of CO2 tension improves short-term respiratory outcome in neonates receiving mechanical ventilation during transport.

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved