PMID: 8598670Feb 1, 1996Paper

Transcutaneous oxygen (TcPO2) estimates probability of healing in the ischemic extremity

The Journal of Surgical Research
F T PadbergR W Hobson

Abstract

The severity of arterial ischemia is a major variable affecting healing of extremity wounds. By relating risk of failure to severity of ischemia, the probability of wound healing may be stratified along with assessment of general medical risks. Transcutaneous oxygen tension (TcPO2) arterial segmental pressure (ASP), and arterial segmental indices (ASI) were obtained in 204 ischemic lower extremity sites; 63% of the sites were in patients with diabetes mellitus (DM), 11% in patients with chronic renal failure (CRF), and 37% in patients with neither DM nor CRF (ND). Wounds included 126 amputations and 78 gangrenous ulcerations of the foot or toes. Healing (n = 112) was defined as complete wound closure, without regard to the time required. Failure (n = 92) was defined by the requirement for either arterial reconstruction (n = 45) or proximal amputation (n = 47). Stepwise multiple regression analysis was used to assess the relative contribution of each measurement and to predict the probability of healing; TcP02 was superior to ASP and ASI in all categories. TcP02 was the only test meeting the P < 0.05 entry criteria modeled by the regression. An accuracy of 83% was achieved. However, when each test was evaluated by univariate ana...Continue Reading

Associated Clinical Trials

Oct 20, 2015·Chandan Sen

Citations

Jun 1, 2011·The Journal of the American College of Certified Wound Specialists·Jayesh B Shah
Jul 25, 2009·PM & R : the Journal of Injury, Function, and Rehabilitation·Robert J Goldman
Nov 15, 2005·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Lisa J GouldShelly Wilson
Jan 21, 2009·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Chandan K Sen
Nov 19, 2011·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Kyle A ArsenaultRichard P Whitlock
Feb 1, 2012·Diabetes/metabolism Research and Reviews·J A P Apelqvist, M J A Lepäntalo
Aug 2, 2011·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Osami KawaradaPeter J Fitzgerald
Jun 28, 2005·Clinics in Podiatric Medicine and Surgery·Keith D Cook
Jun 28, 2005·Clinics in Podiatric Medicine and Surgery·Robert W ZicklerPeter J Pappas
Dec 30, 2011·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·M LepäntaloA H Davies
Dec 6, 2012·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Osami Kawarada
Dec 17, 1998·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·D T Ubbink, M J Jacobs
Jul 27, 2001·Diabetic Medicine : a Journal of the British Diabetic Association·A PfütznerT Kunt
Jun 21, 2002·Annals of the New York Academy of Sciences·Chandan K SenSashwati Roy
May 6, 2005·The International Journal of Lower Extremity Wounds·David K Harrison
Jun 11, 2002·Advances in Skin & Wound Care·Robert J GoldmanMichael A Golden
Apr 12, 2003·Advances in Skin & Wound Care·Robert GoldmanMichael Golden
Jul 9, 2016·Journal of Diabetes Science and Technology·Danielle LowryAlok Tiwari
Jul 23, 2008·Journal of Biomaterials Science. Polymer Edition·William J Lindblad
Aug 21, 2014·Circulation. Cardiovascular Interventions·Osami KawaradaHisao Ogawa
Jul 16, 2015·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Young Hwan KimMan Deuk Kim
Jul 20, 2011·Advances in Skin & Wound Care·Richard SalcidoChulhyun Ahn
Sep 28, 2010·PM & R : the Journal of Injury, Function, and Rehabilitation·Karen L AndrewsVincent Yacyshyn
Aug 23, 2002·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Caroline E FifeJon Mader
Mar 1, 2012·Endocrine·Jan Apelqvist
Jun 27, 2014·Circulation Journal : Official Journal of the Japanese Circulation Society·Osami KawaradaHisao Ogawa
Nov 5, 2003·Current Opinion in Cardiology·Riyaz Bashir, Christopher J Cooper
Jun 20, 2020·The Journal of Clinical Endocrinology and Metabolism·Parinya SamakkarnthaiSundeep Khosla
Jul 13, 2000·Prosthetics and Orthotics International·M Eneroth
Sep 11, 2003·Journal of Wound Care·J L Dobson, S L Ellis
May 7, 2020·The International Journal of Lower Extremity Wounds·Peta Ellen TehanVivienne Helaine Chuter

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.