Transdiagnostic psychopathology mediates the relationship between childhood sexual abuse and HIV/AIDS and other sexually transmitted infections in adulthood

Comprehensive Psychiatry
Jessica A LatackNicholas R Eaton

Abstract

Exposure to childhood sexual abuse (CSA) is associated with elevated rates of mental disorders, sexual risk behavior, and sexually transmitted infections (STIs) in adulthood. Mental disorders themselves are associated with an increased risk for HIV/AIDs and STIs as well, and thus may mediate the association between CSA and HIV/AIDS and other STIs. The links among CSA, disorders, and STIs are unclear, however. The current study tested the hypothesis that the association of CSA with STIs is mediated by adult transdiagnostic psychopathology. We examined the potential mediating role of transdiagnostic psychopathology factors-internalizing (INT) and externalizing (EXT)-in the association between CSA and receiving a past-year diagnosis of HIV, AIDS, or another STI in a large, national probability sample of adults (N=34,653). Using indirect effects modeling, we found that 54.4% of the association between CSA and subsequent HIV/AIDS/STI diagnosis operated through transdiagnostic psychopathology. The proposed mediation model was supported, indicating that individuals reporting CSA had higher estimated levels of latent general liabilities for INT and EXT disorders, and it was largely these liabilities that accounted for the link between ...Continue Reading

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Citations

Sep 13, 2016·Journal of Personality Disorders·Nicholas R EatonDeborah S Hasin
Mar 17, 2017·Drug and Alcohol Dependence·Craig Rodriguez-SeijasNicholas R Eaton
May 7, 2019·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Paolo Fusar-PoliPhilip McGuire
Jan 7, 2021·Journal of Child Sexual Abuse·Amy Dana Ménard, Heather Beth MacIntosh

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