PMID: 799252Dec 22, 1976Paper

Transfer gene expression during fertility inhibition of the Escherichia coli K12 sex factor F by the I-like plasmid R62

Molecular & General Genetics : MGG
M Gasson, N Willetts


Further understanding of how the FinQ fertility inhibition system of the I-like plasmid R62 inhibits transfer of the sex factor F has been gained by the use of a genetic assay for individual transfer gene products. The technique involved construction of a series of Flac plasmids carrying suppressible mutations in individual transfer genes together with a FinQ inhibitor-insensitive traQ mutation. The transfer of the Flac double mutants from a strain carrying wild-type Fhis and R62 then indicated the effect of R62-encoded transfer inhibition on the expression of individual F transfer genes. During such inhibition the products of genes traJ, traA, traE, traB and traC were present in quantities sufficient to permit efficient F transfer, whereas the levels of the traF, traH, traG and traD gene products were so reduced as to limit F transfer. These findings and a failure to obtain recombination between traC and traQ mutations suggest that the R62 fertility inhibition system terminates transcription of the transfer operon between traC and traF.


Mar 1, 1976·Journal of General Microbiology·T J Foster, N S Willetts
Dec 1, 1975·Genetical Research·N WillettsS McIntire
May 1, 1975·Journal of Bacteriology·M J Gasson, N S Willetts
Oct 1, 1974·Journal of Bacteriology·N S Willetts, W Paranchych
Apr 1, 1973·Genetical Research·N S Willetts
Dec 31, 1973·Molecular & General Genetics : MGG·D Finnegan, N Willetts
Jan 1, 1971·Molecular & General Genetics : MGG·D J Finnegan, N S Willetts
Feb 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·A J CLARK, A D MARGULIES

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Jul 25, 1983·Journal of Molecular Biology·D GaffneyN Willetts
Jan 13, 2018·Microbiology Spectrum·María Getino, Fernando de la Cruz
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