Transfer of a large gene regulatory apparatus to a new developmental address in echinoid evolution.

Proceedings of the National Academy of Sciences of the United States of America
Feng Gao, Eric H Davidson

Abstract

Of the five echinoderm classes, only the modern sea urchins (euechinoids) generate a precociously specified embryonic micromere lineage that ingresses before gastrulation and then secretes the biomineral embryonic skeleton. The gene regulatory network (GRN) underlying the specification and differentiation of this lineage is now known. Many of the same differentiation genes as are used in the biomineralization of the embryo skeleton are also used to make the similar biomineral of the spines and test plates of the adult body. Here, we determine the components of the regulatory state upstream of these differentiation genes that are shared between embryonic and adult skeletogenesis. An abrupt "break point" in the micromere GRN is thus revealed, on one side of which most of the regulatory genes are used in both, and on the other side of which the regulatory apparatus is entirely micromere-specific. This reveals the specific linkages of the micromere GRN forged in the evolutionary process by which the skeletogenic gene batteries were caused to be activated in the embryonic micromere lineage. We also show, by comparison with adult skeletogenesis in the sea star, a distant echinoderm outgroup, that the regulatory apparatus responsible ...Continue Reading

References

Jan 1, 1989·Molecular Reproduction and Development·R A CameronE H Davidson
May 1, 1986·The Journal of Cell Biology·S C BensonF Wilt
May 25, 2002·Developmental Biology·Paola OliveriEric H Davidson
Jan 10, 2003·Nature·Hiroaki NakanoShonan Amemiya
Jun 5, 2003·Developmental Biology·Paola OliveriDavid R McClay
Nov 5, 2003·Proceedings of the National Academy of Sciences of the United States of America·Veronica F HinmanEric H Davidson
Feb 14, 2006·Science·Eric H Davidson, Douglas H Erwin
Nov 11, 2006·Science·David J BottjerR Andrew Cameron
Jul 20, 2007·Proceedings of the National Academy of Sciences of the United States of America·Roger Revilla-i-DomingoEric H Davidson
Nov 29, 2007·Proceedings of the National Academy of Sciences of the United States of America·Veronica F Hinman, Eric H Davidson
Apr 17, 2008·Proceedings of the National Academy of Sciences of the United States of America·Paola OliveriEric H Davidson

❮ Previous
Next ❯

Citations

Aug 4, 2010·Development Genes and Evolution·Hiroyuki KogaHiroshi Wada
Jan 14, 2009·Nature Reviews. Genetics·Douglas H Erwin, Eric H Davidson
Oct 14, 2009·Proceedings of the National Academy of Sciences of the United States of America·Joel Smith, Eric H Davidson
Aug 17, 2011·Proceedings of the National Academy of Sciences of the United States of America·José Luis RoyoJosé Luis Gómez-Skarmeta
Jan 13, 2012·Proceedings of the National Academy of Sciences of the United States of America·Sagar S Damle, Eric H Davidson
Jan 8, 2011·BMC Evolutionary Biology·Carlos Espinosa-SotoAndreas Wagner
Nov 26, 2010·Development·Celina E JulianoGary M Wessel
Feb 6, 2009·PLoS Biology·Aditya J SethiLynne M Angerer
Apr 3, 2010·PLoS Computational Biology·Carlos Espinosa-Soto, Andreas Wagner
May 23, 2014·Proceedings. Biological Sciences·Maximilian J TelfordRichard R Copley
May 22, 2013·Proceedings of the National Academy of Sciences of the United States of America·Nuno D PiresLiam Dolan
Apr 21, 2009·The International Journal of Developmental Biology·Isabelle S Peter, Eric H Davidson
Jan 20, 2016·Development Genes and Evolution·Eric M ErkenbrackLaura Romano
Jul 15, 2015·Proceedings of the National Academy of Sciences of the United States of America·Eric M Erkenbrack, Eric H Davidson
Jan 17, 2016·Evolution & Development·Yoshiaki MorinoHiroshi Wada
Aug 2, 2015·Marine Genomics·Tzu-Pei Fan, Yi-Hsien Su
Feb 3, 2015·Developmental Biology·Feng GaoEric H Davidson
Mar 17, 2010·Wiley Interdisciplinary Reviews. Systems Biology and Medicine·Smadar Ben-Tabou de-Leon, Eric H Davidson
May 28, 2009·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Kevin J PetersonMark A McPeek
Oct 13, 2012·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Johannes JaegerNick Monk
Feb 26, 2013·Genesis : the Journal of Genetics and Development·Charles A Ettensohn
Apr 5, 2011·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Rebecca L Young, Günter P Wagner
May 18, 2013·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Orkun S Soyer, Maureen A O'Malley
Mar 1, 2012·Wiley Interdisciplinary Reviews. Developmental Biology·Deirdre C LyonsDavid R McClay
Dec 19, 2009·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Ariel D Chipman
Feb 20, 2014·Genesis : the Journal of Genetics and Development·Veronica F Hinman, Alys M Cheatle Jarvela
Feb 20, 2014·Genesis : the Journal of Genetics and Development·Daniel C McIntyreDavid R McClay
Feb 20, 2014·Genesis : the Journal of Genetics and Development·Hiroyuki KogaHiroshi Wada
Apr 2, 2014·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Jun Tsuchimoto, Masaaki Yamaguchi
Apr 16, 2013·Journal of Structural Biology·Fred WiltPatricia Hamilton
Nov 3, 2009·Developmental Biology·Celina E JulianoGary M Wessel
Feb 16, 2011·Developmental Biology·Eric H Davidson
Apr 26, 2016·Frontiers in Zoology·Anna CzarkwianiPaola Oliveri
Sep 21, 2013·Gene Expression Patterns : GEP·Anna CzarkwianiPaola Oliveri
Dec 3, 2014·Gene Expression Patterns : GEP·Zhongling Sun, Charles A Ettensohn
Mar 19, 2011·Cell·Isabelle S Peter, Eric H Davidson
Jul 9, 2016·Current Opinion in Genetics & Development·Maria Ina ArnoneRossella Annunziata

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
Paola OliveriEric H Davidson
Proceedings of the National Academy of Sciences of the United States of America
Veronica Hinman, Eric H Davidson
Proceedings of the National Academy of Sciences of the United States of America
Roger Revilla-i-DomingoEric H Davidson
Proceedings of the National Academy of Sciences of the United States of America
Veronica HinmanEric H Davidson
© 2022 Meta ULC. All rights reserved