PMID: 591001Dec 1, 1977

Transfer of anaphylactic antibodies from mother to young in the rat

Immunology
A Perrudet-Badoux, R A Binaghi

Abstract

The transfer of anaphylactic antibodies of classes IgE and IgGa from immunized female rats to babies was examined during primary and secondary immunization by injection, and also in rats infested with Trichinella spiralis. IgE antibodies were never detected in the blood of the babies, although they were sometimes detected in the milk in their stomachs. Similarly, no IgE antibodies were found in the serum of babies from mothers infested with Trichinella spiralis during pregnancy. IgGa antibodies were present in the serum and milk of the mothers following secondary immunization, and were readily absorbed through the intestine of the babies.

Related Concepts

Anaphylaxis
Immunoglobulin E
Polyglobin
Variolation
Human Trichinellosis

Related Feeds

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

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