PMID: 9164366May 1, 1997Paper

Transfer of atopy following bone marrow transplantation

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
A BellouD A Moneret-Vautrin

Abstract

Bone marrow transplantation is an optimal treatment of acute leukemia and aplastic anemia. Allergic manifestations in recipients long after bone marrow transplantation have been reported. A case involving transfer of atopy manifested as food allergy-induced-atopic dermatitis is reported. The donor and the patient were investigated by prick tests and RAST to the same food allergens. Single blind, oral challenge to egg documented food allergy in the recipient. A 5-year-old boy without history of atopy developed severe atopic dermatitis after bone marrow transplantation from his HLA-identical sister for acute lymphoblastic leukemia. The patient's course had been marked previously by acute graft versus host disease and cytomegalovirus infection. Immunoallergic evaluation showed an exquisite sensitization to egg, peanut, and soybean. Total IgE was 6400 KIU/L. Concomitantly, the donor showed the same sensitizations. Absolute avoidance resulted in the regression of atopic dermatitis. Subsequently, new sensitization to wheat flour, Dermatophagoides pteronyssinus, birch, and plantain pollens was detected. The donor developed asthma. This case gives evidence of the transfer of sensitization from donor to recipient. The passive transfer o...Continue Reading

References

May 10, 1979·The New England Journal of Medicine·E L ReinherzS F Schlossman
Sep 1, 1991·The Journal of Allergy and Clinical Immunology·D Vercelli, R S Geha
Dec 22, 1988·The New England Journal of Medicine·J M AgostiW R Henderson
Jun 1, 1987·The Journal of Clinical Investigation·S C DreskinJ I Gallin
Jan 12, 1985·British Medical Journal·J TuckerO B Eden
Mar 9, 1985·British Medical Journal·R J ChalmersP Kelsey
Aug 1, 1984·The Journal of Allergy and Clinical Immunology·U M Saarinen
Jan 1, 1981·International Archives of Allergy and Applied Immunology·P G HoltJ Batty
Jan 1, 1994·Annual Review of Immunology·S Romagnani
Mar 24, 1994·The New England Journal of Medicine·J O Armitage

❮ Previous
Next ❯

Citations

Jan 28, 2003·Psycho-oncology·Gurpreet ParmarKa Wah Chan
Apr 29, 2010·Current Allergy and Asthma Reports·Dan Atkins, Jonathan Malka-Rais
Apr 16, 2013·Current Allergy and Asthma Reports·Julia Eckl-Dorna, Verena Niederberger
Apr 7, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·UNKNOWN American College of Allergy, Asthma, & Immunology
Sep 25, 2002·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·John M Kelso
Mar 26, 2003·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A R Gennery, A J Cant
Jul 5, 2007·Journal of Pediatric Hematology/oncology·Shelley Cathcart, Dean Morrell
May 9, 2009·Transplantation·Parsia A VagefiMartin Hertl
Oct 24, 2006·International Archives of Allergy and Immunology·Verena NiederbergerRudolf Valenta
Mar 30, 2013·Allergologia et immunopathologia·J GordonJ Cotliar
Dec 16, 2011·The Journal of Allergy and Clinical Immunology·Melissa DullaersBart N Lambrecht
Jul 11, 2008·American Journal of Ophthalmology·Khalid F TabbaraMahmoud Aljurf
Nov 3, 2005·Clinics in Chest Medicine·Bekele Afessa, Steve G Peters
Jul 17, 2007·Pediatric Transplantation·Jee Hyun LeeSang Il Lee
Aug 29, 2012·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J Eckl-DornaV Niederberger
Oct 30, 2013·Pediatric Transplantation·Evelyn Hsu, Simon Horslen
Mar 30, 2016·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·D M Moutsoglou, S C Dreskin
Jul 13, 2002·Chest·Heather RietzAnthony A Gal
Sep 3, 2014·Transfusion Medicine·A PonnampalamM Bigham
Aug 27, 2014·Current Opinion in Immunology·Lawren C Wu, Heleen Scheerens
Sep 2, 2014·The Journal of Allergy and Clinical Immunology·Hugh A SampsonRobert Wood
Apr 21, 2004·Journal of Pediatric Gastroenterology and Nutrition·Mirna ChehadeNeal S LeLeiko
Mar 26, 2003·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M ShalitR Or
Mar 15, 2014·Nature Reviews. Immunology·Lawren C Wu, Ali A Zarrin
Apr 4, 2018·Pediatrics in Review·Andrea R WaldmanLawrence F Eichenfield
Mar 5, 2019·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·C CarusoS Ginanni Corradini
Aug 31, 2019·Cells·Julia Eckl-DornaRudolf Valenta
Apr 2, 2020·Bone Marrow Transplantation·Sarah WhitesideJan Storek

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.