Transfer of molecular recognition information from DNA nanostructures to gold nanoparticles

Nature Chemistry
Thomas G W EdwardsonHanadi F Sleiman

Abstract

DNA nanotechnology offers unparalleled precision and programmability for the bottom-up organization of materials. This approach relies on pre-assembling a DNA scaffold, typically containing hundreds of different strands, and using it to position functional components. A particularly attractive strategy is to employ DNA nanostructures not as permanent scaffolds, but as transient, reusable templates to transfer essential information to other materials. To our knowledge, this approach, akin to top-down lithography, has not been examined. Here we report a molecular printing strategy that chemically transfers a discrete pattern of DNA strands from a three-dimensional DNA structure to a gold nanoparticle. We show that the particles inherit the DNA sequence configuration encoded in the parent template with high fidelity. This provides control over the number of DNA strands and their relative placement, directionality and sequence asymmetry. Importantly, the nanoparticles produced exhibit the site-specific addressability of DNA nanostructures, and are promising components for energy, information and biomedical applications.

References

Aug 15, 1996·Nature·A P AlivisatosP G Schultz
Mar 28, 2002·Nucleic Acids Research·Zhi LiRobert L Letsinger
Jan 15, 2004·Journal of the American Chemical Society·Hanying LiHao Yan
Dec 8, 2004·PLoS Biology·Paul W K RothemundErik Winfree
Feb 28, 2006·Angewandte Chemie·Faisal A Aldaye, Hanadi F Sleiman
May 20, 2006·Science·Nathaniel L RosiChad A Mirkin
Jul 20, 2006·Journal of the American Chemical Society·Xiaoyang XuChad A Mirkin
Dec 15, 2006·Analytical Chemistry·Sarah J HurstChad A Mirkin
Feb 1, 2008·Nature·Dmytro NykypanchukOleg Gang
Feb 1, 2008·Nature·Sung Yong ParkChad A Mirkin
Mar 31, 2009·Nature Materials·Mathew M MayeOleg Gang
Apr 1, 2009·Journal of the American Chemical Society·Alexander J MastroianniA Paul Alivisatos
May 19, 2009·Journal of the American Chemical Society·Kenji SuzukiMizuo Maeda
Dec 22, 2009·Nature Nanotechnology·Mathew M MayeOleg Gang
Dec 23, 2009·Journal of the American Chemical Society·Karina M M CarneiroHanadi F Sleiman
Feb 19, 2010·Journal of the American Chemical Society·Baoquan DingJeffrey Bokor
Mar 27, 2010·Advanced Drug Delivery Reviews·Jung Heon LeeYi Lu
Oct 30, 2010·Nucleic Acids Research·Prabodhika R MallikaratchyDavid A Scheinberg
Apr 19, 2011·Nature Nanotechnology·Shawn J TanWenlong Cheng
Sep 3, 2011·Angewandte Chemie·Jin-Woo KimRussell Deaton
Sep 10, 2011·Nanoscale·Tao ZhangDongsheng Liu
Oct 11, 2011·Journal of the American Chemical Society·Suchetan PalHao Yan
Oct 15, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Tao ZhangDongsheng Liu
Dec 14, 2011·Journal of the American Chemical Society·Xibo ShenBaoquan Ding
Feb 9, 2012·Journal of the American Chemical Society·Christopher K McLaughlinHanadi F Sleiman
Nov 7, 2012·Nature·Yufeng WangDavid J Pine
Apr 5, 2013·Advanced Materials·Lang FengPaul M Chaikin
Apr 12, 2013·Journal of the American Chemical Society·Sumedh P SurwadeHaitao Liu
Apr 23, 2013·Nano Letters·Xibo ShenBaoquan Ding
Jul 16, 2013·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Jonathan D Halverson, Alexei V Tkachenko
Nov 29, 2013·Nature·Evelyn AuyeungChad A Mirkin
Aug 19, 2014·Nature Nanotechnology·Maxim P NikitinPetr I Nikitin
Oct 18, 2014·Journal of the American Chemical Society·Christopher J SerpellHanadi F Sleiman

❮ Previous
Next ❯

Citations

Mar 5, 2016·Nano Letters·Na Wu, Itamar Willner
Jun 25, 2016·ACS Nano·Robert SchreiberAndrew J Turberfield
Jan 26, 2017·Journal of the American Chemical Society·Janet R McMillanChad A Mirkin
Feb 9, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Christian RossnerPhilipp Vana
Apr 4, 2018·Nature Chemistry·Mahmoud LabibShana O Kelley
Mar 1, 2018·Annual Review of Analytical Chemistry·Dekai YeChunhai Fan
Mar 10, 2018·Chemistry : a European Journal·Dan Guo, Yanlin Song
Nov 7, 2018·Nature Materials·Jie ChaoChunhai Fan
Apr 12, 2019·Chemical Communications : Chem Comm·Yanyan YuHuaping Peng
Apr 27, 2019·Small·Jinyoung SeoJwa-Min Nam
Aug 1, 2019·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Emerald R TaylorChristopher J Serpell
Jul 7, 2017·Chemical Communications : Chem Comm·Akinori KuzuyaMakoto Komiyama
Aug 23, 2019·Chemistry, an Asian Journal·Rémi MérindolSerge Ravaine
Apr 3, 2020·Chemical Communications : Chem Comm·Xiaodong XinYe Tian
Jun 14, 2017·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Bing ZhuChunhai Fan
Dec 25, 2019·Nature Materials·Guangbao YaoChunhai Fan
Aug 25, 2019·Nature Communications·Kathrin HölzMark M Somoza
Aug 18, 2017·Chemical Communications : Chem Comm·Gaoli ChenZhaoxiang Deng
Sep 13, 2017·Frontiers in Cell and Developmental Biology·Angela Re
Oct 24, 2017·Angewandte Chemie·Jianlei ShenChunhai Fan
Oct 17, 2018·Nanoscale·Laurent Lermusiaux, Alison M Funston
May 22, 2019·Annual Review of Physical Chemistry·Maximilian J UrbanNa Liu
Jan 18, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Anna GraczykArkadiusz Chworos
Jun 26, 2020·Nature Materials·Shuoxing JiangHao Yan
Dec 5, 2018·Nature Materials·Gang ChenYossi Weizmann
Aug 14, 2019·Chemical Society Reviews·Wenjing WangJun-Jie Zhu
May 10, 2020·Nature Communications·Sha SunOleg Gang
Sep 12, 2020·Science·Oleg Gang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Angewandte Chemie
Zhaoxiang Deng, Chengde Mao
Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
Ishtiaq Saaem, Thomas H LaBean
© 2022 Meta ULC. All rights reserved