PMID: 4894689Apr 1, 1969Paper

Transfer RNA methylases during morphogenesis in the cellular slime mold

Proceedings of the National Academy of Sciences of the United States of America
D J Pillinger, E Borek

Abstract

The enzymes that methylate tRNA were studied during the life cycle of the colonizing slime mold, Dictyostelium discoideum. Total and base specific tRNA methylase activities were determined in extracts from cells in morphogenetic synchrony. Eight hours after enforced aggregation, the total methylase capacity is reduced by about 40 per cent. The diminution appears to be due to the presence of inhibitors that do not inhibit the base specific enzymes to the same extent. There is a still greater diminution in enzyme activity in extracts of the mature fruiting bodies.

References

Apr 22, 1968·Biochimica Et Biophysica Acta·A M Kaye, P S Leboy
Feb 1, 1967·Biochemistry·R RodehU Z Littauer
Nov 17, 1967·Biochemical and Biophysical Research Communications·J A BoeziM De Backer
May 10, 1968·Biochemical and Biophysical Research Communications·L ShugartM P Stulberg
Nov 1, 1964·Proceedings of the National Academy of Sciences of the United States of America·A PETERKOFSKY
Nov 30, 1967·Biochemical and Biophysical Research Communications·G F Vande WoudeJ Polatnick

❮ Previous
Next ❯

Citations

May 23, 2000·Biotechnology and Bioengineering·D W KahnM E Winkler
Dec 10, 1976·Mycopathologia·D Gottlieb, K Raghu
Jul 29, 1971·Biochimica Et Biophysica Acta·O K SharmaE Borek
Dec 1, 1976·Developmental Biology·R E LawS K Shapiro
Mar 8, 1971·Life Sciences. Pt. 2: Biochemistry, General and Molecular Biology·D J Pillinger, R Wilkinson
Jan 1, 1973·Advances in Enzyme Regulation·S J Kerr, E Borek
Apr 8, 1971·Biochimica Et Biophysica Acta·A E Pegg
Apr 25, 1975·Journal of Molecular Biology·M T Clandinin, G A Schultz
Jul 15, 1971·FEBS Letters·A E. Pegg
Dec 26, 1970·Nature·V M Craddock
Nov 15, 1971·International Journal of Cancer. Journal International Du Cancer·R Wilkinson, D J Pillinger
Apr 1, 1972·Journal of Pharmaceutical Sciences·C C Cheng

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.