PMID: 6171226Sep 1, 1981Paper

Transformation of rat fibroblasts by cloned defective polyoma DNA

Archives internationales de physiologie et de biochimie
C Parent, M Bastin

Abstract

Defective polyoma DNA molecules isolated from mouse cells infected with high-multiplicity-passaged virus were cloned in pBR322, and the recombinant plasmids were tested for their capacity to transform Fischer rat 3T3 cells in culture. Recombinants carrying an intact proximal portion of the early region, i.e., the region coding for both small and middle T antigens, were able to induce the transformed phenotype. A recombinant plasmid containing a defective polyoma genome with a deletion of about 300 base pairs in the region coding for the C-terminal segment of middle T antigen failed to transform.

References

Oct 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·Y ItoR Dulbecco
Jan 1, 1975·Cold Spring Harbor Symposia on Quantitative Biology·R KamenR W Old
Jan 1, 1975·Cold Spring Harbor Symposia on Quantitative Biology·M FriedD L Robberson
Jun 1, 1976·Journal of Virology·L K Miller, M Fried
Nov 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·J FeunteunT Benjamin
Dec 1, 1976·The Journal of General Virology·N D Stow, N M Wilkie
Aug 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·M A IsraelM A Martin
Nov 1, 1979·Journal of Virology·G Magnusson, P Berg
Sep 1, 1979·Journal of Virology·B E Griffin, C Maddock
Jun 14, 1967·Journal of Molecular Biology·B Hirt
Sep 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·T L Benjamin
May 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·B E GriffinA Cowie
May 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·R RadloffJ Vinograd
Mar 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·J L MooreM A Israel
Jul 1, 1980·Journal of Virology·M A IsraelR Pollack
Jun 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·U NovakB E Griffin
Jan 1, 1980·Cold Spring Harbor Symposia on Quantitative Biology·Y Ito, N Spurr
Jan 1, 1980·Cold Spring Harbor Symposia on Quantitative Biology·L V Crawford
Jul 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·J A HassellP E Moreau
Sep 1, 1980·The Journal of General Virology·M BastinP Bourgaux

❮ Previous
Next ❯

Related Concepts

Related Feeds

BK Virus Infection

BK virus infection is a significant complication of modern immunosuppression used in kidney transplantation. Discover the latest research on BK virus infection here.