PMID: 9545427Apr 18, 1998Paper

Transforming the cell surface through proteolysis

Chemistry & Biology
L L Kiessling, E J Gordon

Abstract

Protein shedding, or the proteolytic cleavage of a protein from the surface of a cell, is emerging as an important mechanism in the regulation of cellular activity but it is poorly understood. Growing evidence suggesting that protein shedding and protein function are closely linked may lead to new strategies for the treatment of a wide range of diseases.

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