Transfusion practice varies widely in cardiac surgery: Results from a national registry

The Journal of Thoracic and Cardiovascular Surgery
Zoe K McQuiltenLouise Phillips

Abstract

Evidence is accumulating of adverse outcomes associated with transfusion of blood components. If there are differences in perioperative transfusion rates in cardiac surgery, and what hospital factors may contribute, requires further investigation. Analysis of 42,743 adult patients who underwent 43,482 procedures from 2005 to 2011 at 25 Australian hospitals, according to the Australian and New Zealand Society of Cardiac and Thoracic Surgeons Cardiac Surgery Database. Multiple logistic regression examined associations of patient and hospital characteristics with transfusion of ≥1 red blood cell (RBC) unit; platelet (PLT), fresh frozen plasma (FFP), and cryoprecipitate (CRYO) doses; and ≥5 RBC units, from surgery until hospital discharge. Procedures included 24,222 (55%) isolated coronary artery bypass grafts, 7299 (17%) isolated valve, 4714 (11%) coronary artery bypass graft and valve, and 7247 (17%) other procedures. After adjustment for various patient and procedure characteristics, transfusion rates varied across hospitals for ≥1 RBC unit from 22% to 67%, ≥5 RBC units from 5% to 25%, ≥1 PLT dose from 11% to 39%, ≥1 FFP dose from 11% to 48% and ≥1 CRYO dose from 1% to 20%. Hospital characteristics, including state or territory,...Continue Reading

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Citations

Oct 27, 2016·ANZ Journal of Surgery·Jay RobertsBoon Kua
Mar 1, 2016·Heart, Lung & Circulation·Andrew D CochraneJulian A Smith
Sep 20, 2016·Journal of Cardiothoracic and Vascular Anesthesia·Domenico CalcaterraAryeh Shander
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May 19, 2017·World Journal of Cardiology·Mohsen KarimiAnil Mathew
Apr 13, 2020·General Thoracic and Cardiovascular Surgery·Alexandra A HeimisdottirTomas Gudbjartsson
Mar 13, 2019·Journal of Cardiothoracic and Vascular Anesthesia·Marine HubertClaude Ecoffey
Oct 12, 2019·The Thoracic and Cardiovascular Surgeon·Mirna PetricevicBojan Biocina
Jun 27, 2019·The Journal of Thoracic and Cardiovascular Surgery·Dhaval KolteAfshin Ehsan

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