Transfusion-Related Acute Lung Injury During Liver Transplantation: A Scoping Review.

Journal of Cardiothoracic and Vascular Anesthesia
Manoj H IyerAntolin S Flores

Abstract

Liver transplantation is associated with significant blood loss, often requiring massive blood product transfusion. Transfusion-related acute lung injury (TRALI) is a devastating cause of transfusion-related deaths. While reports have investigated the general incidence of TRALI, the incidence of TRALI specifically following transfusion during liver transplant remains unclear. This scoping review summarizes existing literature regarding TRALI during the liver transplantation perioperative period. Databases were searched for all articles and abstracts reporting on TRALI after liver transplantation. Data collected included number of patients studied, patient characteristics, incidences of TRALI, TRALI characteristics, and patient outcomes. The primary outcome investigated was the incidence of TRALI in the setting of liver transplantation. Thirteen full-text citations were included in this review. The incidence of TRALI post-liver transplant was 0.68% (65 of 9,554). Based on reported transfusion data, patients diagnosed with TRALI received an average of 10.92 ± 10.81 units of packed red blood cells (pRBC), 20.05 ± 15.72 units of fresh frozen plasma, and 5.75 ± 10.00 units of platelets. Common interventions following TRALI diagnosis...Continue Reading

References

Nov 1, 1986·Transplantation·W A JensenC Trey
May 1, 1993·Mayo Clinic Proceedings·B AfessaM J Krowka
Jul 29, 2000·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·C P SnowdenD R Roberts
Mar 29, 2001·Transfusion·M A Popovsky, R D Davenport
Oct 19, 2001·Transfusion·P M KopkoP V Holland
Nov 23, 2006·Transplantation Proceedings·S K HongT Y Ha
Feb 24, 2007·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·E SykesC B O'Suilleabhain
Jun 15, 2007·Transfusion Medicine·J D KrochmalA J Schlueter
Jul 27, 2007·Best Practice & Research. Clinical Anaesthesiology·Pearl Toy, Clifford Lowell
Sep 22, 2010·Implementation Science : IS·Danielle LevacKelly K O'Brien
Feb 1, 2011·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Alexander B BensonMarc Moss
May 4, 2011·Revista española de anestesiología y reanimación·J RomanoP Monedero
Jul 28, 2011·Anesthesiology·Brian M GillissMichael A Gropper
Nov 26, 2011·Blood·Pearl ToyUNKNOWN TRALI Study Group
Aug 13, 2013·Seminars in Respiratory and Critical Care Medicine·Enrique Ortiz-DiazJoseph E Levitt
Jan 11, 2014·World Journal of Gastroenterology : WJG·Paolo FeltraccoCarlo Ori
Dec 24, 2014·Indian Journal of Anaesthesia·Sandeep SahuAnupam Verma
Jun 30, 2015·Transplantation Reviews·Aparna Dalal
Nov 29, 2015·Journal of Autoimmunity·Qixia WangXiong Ma
Jan 29, 2016·World Journal of Gastroenterology : WJG·Matthias HartmannFuat H Saner
Feb 9, 2016·Expert Review of Hematology·Sofiane TariketFabrice Cognasse
Sep 27, 2016·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Kuang-Cheng ChanYa-Jung Cheng
Nov 16, 2016·Clinics in Chest Medicine·Gregory A Schmidt
Aug 9, 2017·Anesthesiology Clinics·Dieter AdelmannMichael A Ramsay
Aug 31, 2017·Journal of Translational Medicine·Guo-Wei TuZhe Luo
Mar 20, 2018·Journal of Intensive Care Medicine·Justin K LuiScott E Kopec
Sep 5, 2018·Annals of Internal Medicine·Andrea C TriccoSharon E Straus
Aug 14, 2019·Anesthesiology·Mark J McVeyWolfgang M Kuebler
Apr 27, 2020·Best Practice & Research. Clinical Anaesthesiology·Carolyn ThaiGebhard Wagener

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