Transfusion-transmitted hepatitis E in a 'nonhyperendemic' country

Transfusion Medicine
E BoxallC-G Teo

Abstract

Indigenous hepatitis E is increasingly recognized in developed countries, where it may be a zoonosis. We describe the first case of transfusion-transmitted hepatitis E in the UK from a blood donor who had no history of recent travel abroad. Follow-up of the donor and recipients of the blood products was carried out using serological and molecular techniques. Acute hepatitis E was transmitted to one of two recipients. The infected patient would have received a larger volume of the donor's plasma. HEV subgenomic sequences carried by the donor and recipient were identical. This is the first case of post-transfusion hepatitis E in the UK. Secondary transmission of hepatitis E indigenous to a nonhyperendemic country may occur by blood transfusion. It is important that blood donors inform the transfusion service of all post-donation illnesses so that appropriate interventions can take place.

References

May 1, 1992·Journal of Medical Virology·S J SkidmoreG R Reyes
Mar 27, 1993·Lancet·H L ZaaijerH J van der Pal
Mar 1, 1996·Journal of Viral Hepatitis·S J Skidmore, L M Sherratt
Sep 2, 1997·Proceedings of the National Academy of Sciences of the United States of America·X J MengS U Emerson
Feb 18, 1999·Journal of Medical Virology·G G SchlauderI K Mushahwar
Jul 8, 1999·Liver·T J Harrison
Oct 19, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E SchwartzE Galun
Jun 18, 2004·Emerging Infectious Diseases·Malcolm BanksHarry Dalton
Jun 24, 2004·Journal of Gastroenterology and Hepatology·Mohammad Sultan KhurooGhulam Nabi Yattoo
Sep 16, 2004·Journal of Medical Virology·Jean Michel MansuyJacques Izopet

❮ Previous
Next ❯

Citations

Jan 11, 2008·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·UNKNOWN Arbeitskreis Blut des Bundesministeriums für Gesundheit
May 14, 2009·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·S Schaefer
Sep 28, 2012·The New England Journal of Medicine·Jay H HoofnagleRobert H Purcell
Jan 9, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jean-Michel MansuyJacques Izopet
Apr 7, 2007·Current Opinion in Gastroenterology·Jessica Tan, Anna Sf Lok
Jul 17, 2013·Transplantation·Audrey CoillyAnne-Marie Roque-Afonso
Mar 22, 2013·Journal of Clinical Microbiology·Florence AbravanelJacques Izopet
Jun 8, 2012·Journal of Clinical Microbiology·Tanja VollmerJens Dreier
Jan 1, 2008·Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur̈ Transfusionsmedizin Und Immunham̈atologie·Georg PauliCarl-Heinz Wirsing von König
Jun 8, 2007·Journal of Translational Medicine·Florian BihlChristian Brander
Aug 10, 2013·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·E SlotH L Zaaijer
Jun 15, 2007·Emerging Infectious Diseases·Philippe ColsonCatherine Tamalet
May 8, 2013·Emerging Infectious Diseases·Sally A BaylisUNKNOWN HEV Collaborative Study Group
Sep 28, 2013·International Journal of Environmental Research and Public Health·Danielle M Yugo, Xiang-Jin Meng
Mar 13, 2012·World Journal of Gastroenterology : WJG·Xian-Feng ChengLing-Fei Han
Nov 28, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Pavel ChalupaMichal Holub
Jan 1, 2011·Case Reports in Transplantation·Hui-Hui TanChee-Kiat Tan
Jan 1, 2014·Antiviral Research·Yannick Debing, Johan Neyts
May 3, 2014·BMJ Case Reports·Marijke A de VriesJohannes M M Boots
Jul 1, 2014·Hepatitis Monthly·Cosme Alvarado-EsquivelJesus Hernandez-Tinoco
Jun 7, 2014·BMC Infectious Diseases·Jong-Hoon KimThomas F Wierzba
Mar 4, 2014·Current Infectious Disease Reports·Harry R DaltonAnnemiek A van der Eijk
Oct 24, 2014·Emerging Infectious Diseases·Pierre GallianJacques Izopet
Oct 30, 2012·Journal of Gastroenterology·Hiroaki Okamoto
Jan 20, 2016·Transfusion clinique et biologique : journal de la Société française de transfusion sanguine·B Pozzetto, O Garraud
Oct 31, 2015·International Journal of Molecular Sciences·Daniele LapaAnna Rosa Garbuglia
Apr 24, 2013·Médecine et maladies infectieuses·F AbravanelJ Izopet
Apr 26, 2016·Hepatitis Monthly·Khashayar HesamizadehMaryam Keshvari
Apr 28, 2012·Gastroenterology·Heiner WedemeyerMichael P Manns
May 24, 2011·Virus Research·Michael A Purdy, Yury E Khudyakov
Mar 19, 2011·Transfusion clinique et biologique : journal de la Société française de transfusion sanguine·B Pozzetto, O Garraud
Apr 2, 2010·American Journal of Preventive Medicine·Sean R TrimbleNimia Reyes
Sep 19, 2009·Gastroentérologie Clinique Et Biologique·C RenouN Pavio
Jun 27, 2009·Vox Sanguinis·C AdlhochH Meisel

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.