PMID: 11604580Oct 18, 2001Paper

Transfusion triggers for blood components

Current Opinion in Hematology
P Clark, P D Mintz

Abstract

Whereas there are general guidelines for acceptable transfusion therapy, optimal transfusion therapy has not been determined for most clinical settings. Recent research has focused on controlled studies of red cell transfusion in specific clinical settings. Better determinations of oxygen delivery and consumption are needed to guide clinicians in determining whether transfusion is justified for patients during the perioperative period, those with coronary artery disease, and those in intensive care units. For sickle cell disease, the role of transfusion for acute complications can be life saving; however, the role of chronic transfusion regimens awaits further research into efficacy. Finally, whereas criteria for the prophylactic transfusion of platelets in hematologic diseases are well described, relatively little information is available on the value of platelet transfusion where the absolute count is less than 100,000 but greater than 50,000. The value of fresh frozen plasma components, both standard and sterilized, also requires elucidation.

References

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Citations

Nov 26, 2009·AJR. American Journal of Roentgenology·Stacy D O'ConnorThomas C Winter
May 30, 2012·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Nilgün AltuntasYıldız Atalay
Sep 5, 2009·International Journal of Obstetric Anesthesia·J ParkerS Stanworth
Aug 29, 2007·Pharmacotherapy·Aryeh Shander, Lawrence T Goodnough
Sep 15, 2016·Oral and Maxillofacial Surgery Clinics of North America·Regina L Landesberg, Elie M Ferneini
Mar 14, 2019·Clinical Spine Surgery : a Spine Publication·Taylor E PurvisDaniel M Sciubba

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