Transgenic technologies to induce sterility.

Malaria Journal
Flaminia CatterucciaErnst A Wimmer

Abstract

The last few years have witnessed a considerable expansion in the number of tools available to perform molecular and genetic studies on the genome of Anopheles mosquitoes, the vectors of human malaria. As a consequence, knowledge of aspects of the biology of mosquitoes, such as immunity, reproduction and behaviour, that are relevant to their ability to transmit disease is rapidly increasing, and could be translated into concrete benefits for malaria control strategies. Amongst the most important scientific advances, the development of transgenic technologies for Anopheles mosquitoes provides a crucial opportunity to improve current vector control measures or design novel ones. In particular, the use of genetic modification of the mosquito genome could provide for a more effective deployment of the sterile insect technique (SIT) against vector populations in the field. Currently, SIT relies on the release of radiation sterilized males, which compete with wild males for mating with wild females. The induction of sterility in males through the genetic manipulation of the mosquito genome, already achieved in a number of other insect species, could eliminate the need for radiation and increase the efficiency of SIT-based strategies....Continue Reading

References

Jun 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·M Gossen, H Bujard
Aug 1, 1985·Journal of Economic Entomology·J D Lines, C F Curtis
Apr 1, 1967·Animal Behaviour·A Manning
Feb 1, 1997·Molecular and Cellular Biology·D VucicL K Miller
Mar 1, 1997·Insect Biochemistry and Molecular Biology·M F Wolfner
Feb 21, 1998·The EMBO Journal·E K EvansS Kornbluth
Dec 19, 1998·The EMBO Journal·C ClaveríaM Torres
Apr 29, 1999·Proceedings of the National Academy of Sciences of the United States of America·W N HainingH Steller
Oct 8, 1999·Trends in Cell Biology·J M Abrams
Dec 28, 1999·Trends in Cell Biology·Z Song, H Steller
Jul 13, 2000·Proceedings of the National Academy of Sciences of the United States of America·J C Heinrich, M J Scott
May 25, 2002·Nature·Junitsu ItoMarcelo Jacobs-Lorena
May 30, 2002·Molecular and Biochemical Parasitology·Luke Alphey, Morten Andreasen
Jun 22, 2002·Proceedings of the National Academy of Sciences of the United States of America·George DimopoulosFotis C Kafatos
Aug 22, 2002·EMBO Reports·Stéphanie BlandinElena A Levashina
Sep 13, 2002·Insect Biochemistry and Molecular Biology·Luke Alphey
Sep 27, 2002·Genesis : the Journal of Genetics and Development·Krishna MelnatturJohn R Nambu
Oct 5, 2002·Science·Robert A HoltStephen L Hoffman
Oct 5, 2002·Science·Catherine A HillLaurence J Zwiebel
Dec 17, 2002·Nature Biotechnology·Carsten Horn, Ernst A Wimmer
Aug 5, 2003·Proceedings of the National Academy of Sciences of the United States of America·Huanfa Liu, Eric Kubli
Aug 7, 2003·Trends in Parasitology·Mark Q Benedict, Alan S Robinson
Oct 9, 1959·Science·E F KNIPLING
Mar 27, 2004·Science·Mike A OstaFotis C Kafatos
Dec 21, 2004·Journal of Medical Entomology·Akio MoriDavid W Severson
Sep 2, 2005·Medical and Veterinary Entomology·M H Andreasen, C F Curtis
Oct 26, 2005·Nature Biotechnology·Flaminia CatterucciaAndrea Crisanti
Feb 14, 2006·Insect Molecular Biology·O MarinottiA A James
May 17, 2006·Malaria Journal·Michelle E H HelinskiBart G J Knols

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Citations

Dec 16, 2009·Malaria Journal·Alan S RobinsonJorge Hendrichs
Dec 16, 2009·Malaria Journal·Michelle E H HelinskiBart G J Knols
Jul 18, 2012·PLoS Neglected Tropical Diseases·Geneviève M C LabbéLuke Alphey
Jul 1, 2011·Tropical Parasitology·Se DamodaranSuresh Chandra Pradhan
Apr 14, 2010·Transgenic Research·Holly J FergusonMalcolm Fraser
Apr 17, 2012·Expert Opinion on Biological Therapy·Eric P Caragata, Thomas Walker
Nov 21, 2013·Pest Management Science·Bp Niranjan ReddyB Prasad Rao
May 25, 2013·Current Biology : CB·Ernst A Wimmer
Aug 13, 2013·Acta Tropica·Yael Leah Dahan, Lizette Leonie Koekemoer
Feb 12, 2014·Acta Tropica·Danilo Oliveira CarvalhoMargareth Lara Capurro
Sep 17, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kimberly E MaceJacek Skarbinski
Jul 3, 2015·PLoS Neglected Tropical Diseases·Danilo O CarvalhoMargareth L Capurro
Dec 24, 2016·International Journal of Environmental Research and Public Health·Kristina K Gonzales, Immo A Hansen
Jul 11, 2019·Proceedings. Biological Sciences·Jiangtao Liang, Igor V Sharakhov
Jan 4, 2018·DNA and Cell Biology·Michaela J SchultzHoracio M Frydman
Dec 14, 2018·Scientific Reports·Joana MarquesHenrique Silveira
Mar 7, 2020·RNA Biology·Hewawasam Patuwatha Badathuruge Kalindu Dulanja RamyasomaYasanthi Illika Nilmini Silva Gunawardene
Feb 22, 2021·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Jing-Xiang ChenWen-Qing Zhang
Mar 9, 2019·G3 : Genes - Genomes - Genetics·William Bart BryantKristin Michel
May 8, 2021·Royal Society Open Science·Geoffrey R HosackKeith R Hayes

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Methods Mentioned

BETA
genetic modification
transgenic
X-ray
PCR
transgenics

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